Postmortem imaging in goats using computed tomography with air as a negative contrast agent.


Journal

PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081

Informations de publication

Date de publication:
2019
Historique:
received: 30 11 2018
accepted: 08 04 2019
entrez: 24 4 2019
pubmed: 24 4 2019
medline: 15 2 2020
Statut: epublish

Résumé

Evaluation of the usefulness of air as a negative contrast medium of blood vessels in goats in post mortem computed tomography (PMCT) and establishing the protocol with appropriate doses and timing of the contrast medium administration. Thirty three goats were euthanized 10 to 300 min before the study. First, in 3 goats air was administered into the left or right common carotid artery at dose of 60, 100 and 120 ml/kg, and after each dose PMCT was performed in lateral recumbency. As the latter dose proved to visualize blood vessels best, following 30 goats were examined in the same manner but only with the use of air dose of 120 ml/kg. The quality of CT scans was evaluated independently by two board-certified radiologists. In all studied animals the vascular system filled with air was clearly visualized on CT scans. In most of goats this amount of air revealed vessels smaller than 4 mm in diameter. PMCT with air as a negative contrast agent may be an alternative technique used in post-mortem angiography.

Identifiants

pubmed: 31013296
doi: 10.1371/journal.pone.0215758
pii: PONE-D-18-32311
pmc: PMC6478312
doi:

Substances chimiques

Contrast Media 0

Types de publication

Evaluation Study Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0215758

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

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Auteurs

Olga Szaluś-Jordanow (O)

Department of Small Animal Diseases with Clinic, Faculty of Veterinary Medicine, Warsaw University of Life Sciences-SGGW, Warsaw, Poland.

Joanna Bonecka (J)

Department of Small Animal Diseases with Clinic, Faculty of Veterinary Medicine, Warsaw University of Life Sciences-SGGW, Warsaw, Poland.

Filip Pankowski (F)

Department of Morphological Sciences, Faculty of Veterinary Medicine, Warsaw University of Life Sciences-SGGW, Warsaw, Poland.

Karolina Barszcz (K)

Department of Morphological Sciences, Faculty of Veterinary Medicine, Warsaw University of Life Sciences-SGGW, Warsaw, Poland.

Sylwia Tarka (S)

Department of Forensic Medicine, Medical University of Warsaw, Warsaw, Poland.

Magdalena Kwiatkowska (M)

Department of Forensic Medicine, Medical University of Warsaw, Warsaw, Poland.

Michał Polguj (M)

Department of Angiology, Medical University of Łódź, Łódź, Poland.

Marcin Mickiewicz (M)

Laboratory of Veterinary Epidemiology and Economics, Warsaw University of Life Sciences-SGGW, Warsaw, Poland.

Agata Moroz (A)

Laboratory of Veterinary Epidemiology and Economics, Warsaw University of Life Sciences-SGGW, Warsaw, Poland.

Michał Czopowicz (M)

Laboratory of Veterinary Epidemiology and Economics, Warsaw University of Life Sciences-SGGW, Warsaw, Poland.

Tadeusz Frymus (T)

Department of Small Animal Diseases with Clinic, Faculty of Veterinary Medicine, Warsaw University of Life Sciences-SGGW, Warsaw, Poland.

Jarosław Kaba (J)

Laboratory of Veterinary Epidemiology and Economics, Warsaw University of Life Sciences-SGGW, Warsaw, Poland.

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Classifications MeSH