Proximity biotinylation identifies a set of conformation-specific interactions between Merlin and cell junction proteins.


Journal

Science signaling
ISSN: 1937-9145
Titre abrégé: Sci Signal
Pays: United States
ID NLM: 101465400

Informations de publication

Date de publication:
23 04 2019
Historique:
entrez: 25 4 2019
pubmed: 25 4 2019
medline: 1 7 2020
Statut: epublish

Résumé

Neurofibromatosis type 2 is an inherited, neoplastic disease associated with schwannomas, meningiomas, and ependymomas and that is caused by inactivation of the tumor suppressor gene

Identifiants

pubmed: 31015291
pii: 12/578/eaau8749
doi: 10.1126/scisignal.aau8749
pmc: PMC6631321
mid: NIHMS1026173
pii:
doi:

Substances chimiques

Apoptosis Regulatory Proteins 0
Phosphatidylinositol 4,5-Diphosphate 0
TP53BP2 protein, human 0
Trp53bp2 protein, mouse 0
Tumor Suppressor Proteins 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : NINDS NIH HHS
ID : R37 NS083580
Pays : United States
Organisme : NIGMS NIH HHS
ID : T32 GM063483
Pays : United States

Informations de copyright

Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

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Auteurs

Robert F Hennigan (RF)

Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital, Cincinnati, OH 45229, USA. robert.hennigan@cchmc.org.

Jonathan S Fletcher (JS)

Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital, Cincinnati, OH 45229, USA.

Steven Guard (S)

Department of Molecular, Cellular & Developmental Biology, University of Colorado Boulder, Boulder, CO 80309, USA.

Nancy Ratner (N)

Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital, Cincinnati, OH 45229, USA.

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Classifications MeSH