Proximity biotinylation identifies a set of conformation-specific interactions between Merlin and cell junction proteins.
Animals
Apoptosis Regulatory Proteins
/ genetics
Biotinylation
Cell Line, Transformed
Humans
Intercellular Junctions
/ genetics
Mechanotransduction, Cellular
Mice
Neurofibromatosis 2
/ genetics
Phosphatidylinositol 4,5-Diphosphate
/ genetics
Protein Domains
Schwann Cells
/ metabolism
Tumor Suppressor Proteins
/ genetics
Journal
Science signaling
ISSN: 1937-9145
Titre abrégé: Sci Signal
Pays: United States
ID NLM: 101465400
Informations de publication
Date de publication:
23 04 2019
23 04 2019
Historique:
entrez:
25
4
2019
pubmed:
25
4
2019
medline:
1
7
2020
Statut:
epublish
Résumé
Neurofibromatosis type 2 is an inherited, neoplastic disease associated with schwannomas, meningiomas, and ependymomas and that is caused by inactivation of the tumor suppressor gene
Identifiants
pubmed: 31015291
pii: 12/578/eaau8749
doi: 10.1126/scisignal.aau8749
pmc: PMC6631321
mid: NIHMS1026173
pii:
doi:
Substances chimiques
Apoptosis Regulatory Proteins
0
Phosphatidylinositol 4,5-Diphosphate
0
TP53BP2 protein, human
0
Trp53bp2 protein, mouse
0
Tumor Suppressor Proteins
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, U.S. Gov't, Non-P.H.S.
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : NINDS NIH HHS
ID : R37 NS083580
Pays : United States
Organisme : NIGMS NIH HHS
ID : T32 GM063483
Pays : United States
Informations de copyright
Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.
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