Inverse Occlusion: A Binocularly Motivated Treatment for Amblyopia.
Journal
Neural plasticity
ISSN: 1687-5443
Titre abrégé: Neural Plast
Pays: United States
ID NLM: 100883417
Informations de publication
Date de publication:
2019
2019
Historique:
received:
15
09
2018
revised:
23
11
2018
accepted:
08
01
2019
entrez:
25
4
2019
pubmed:
25
4
2019
medline:
18
12
2019
Statut:
epublish
Résumé
Recent laboratory findings suggest that short-term patching of the amblyopic eye (i.e., inverse occlusion) results in a larger and more sustained improvement in the binocular balance compared with normal controls. In this study, we investigate the cumulative effects of the short-term inverse occlusion in adults and old children with amblyopia. This is a prospective cohort study of 18 amblyopes (10-35 years old; 2 with strabismus) who have been subjected to 2 hours/day of inverse occlusion for 2 months. Patients who required refractive correction or whose refractive correction needed updating were given a 2-month period of refractive adaptation. The primary outcome measure was the binocular balance which was measured using a phase combination task; the secondary outcome measures were the best-corrected visual acuity which was measured with a Tumbling E acuity chart and converted to logMAR units and the stereoacuity which was measured with the Random-dot preschool stereogram test. The average binocular gain was 0.11 in terms of the effective contrast ratio (
Identifiants
pubmed: 31015829
doi: 10.1155/2019/5157628
pmc: PMC6444262
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
5157628Références
Arch Ophthalmol. 2002 Mar;120(3):268-78
pubmed: 11879129
Am J Ophthalmol. 2018 Feb;186:104-115
pubmed: 29196184
Vision Res. 2015 Sep;114:56-67
pubmed: 25637856
Br J Ophthalmol. 1968 Nov;52(11):839-42
pubmed: 5696912
Invest Ophthalmol Vis Sci. 2016 Aug 1;57(10):4450-1
pubmed: 27557437
Neuroscience. 2017 Dec 26;367:127-133
pubmed: 29111363
Spat Vis. 1997;10(4):437-42
pubmed: 9176953
Arch Ophthalmol. 2005 Apr;123(4):437-47
pubmed: 15824215
Curr Biol. 2015 Dec 7;25(23):R1122-3
pubmed: 26654367
JAMA Ophthalmol. 2014 Jul;132(7):799-805
pubmed: 24789375
Spat Vis. 1997;10(4):433-6
pubmed: 9176952
Arch Ophthalmol. 1965 Jun;73:776-81
pubmed: 14302508
Curr Biol. 2015 Jun 1;25(11):1496-501
pubmed: 26004760
J AAPOS. 2004 Oct;8(5):420-8
pubmed: 15492733
Curr Biol. 2011 Jul 26;21(14):R538-9
pubmed: 21783029
J AAPOS. 2015 Oct;19(5):401-5
pubmed: 26486019
J Vis. 2013 Apr 22;13(5):19
pubmed: 23608341
Invest Ophthalmol Vis Sci. 2018 Aug 1;59(10):4190-4197
pubmed: 30128490
Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1966 Aug 15;170(3):257-64
pubmed: 5300850
JAMA Ophthalmol. 2016 Dec 01;134(12):1402-1408
pubmed: 27832248
J AAPOS. 2015 Feb;19(1):6-11
pubmed: 25727578
Invest Ophthalmol Vis Sci. 2013 Sep 17;54(9):6158-66
pubmed: 23882695
J Vis. 2013 Apr 18;13(5):
pubmed: 23599416
Am Orthopt J. 1967;17:56-61
pubmed: 6035874
Neural Plast. 2017;2017:4780876
pubmed: 28357142
Nature. 2001 Jul 5;412(6842):79-83
pubmed: 11452310
Sci Rep. 2018 Nov 20;8(1):17083
pubmed: 30459412
Proc Natl Acad Sci U S A. 2006 Jan 24;103(4):1141-6
pubmed: 16410354
Ophthalmology. 2013 Nov;120(11):2270-7
pubmed: 23755872
Sci Rep. 2017 Jan 10;7:39913
pubmed: 28071682
Science. 2008 Apr 18;320(5874):385-8
pubmed: 18420937
Ophthalmology. 2010 May;117(5):998-1004.e6
pubmed: 20163869
Ophthalmology. 2006 Nov;113(11):2097-100
pubmed: 17074568
Eye (Lond). 2002 Mar;16(2):150-5
pubmed: 11988815
Clin Exp Optom. 2018 Jul;101(4):431-442
pubmed: 29392811
Restor Neurol Neurosci. 2015;33(3):381-7
pubmed: 26410580
J Vis. 2013 May 01;13(6):
pubmed: 23637272
Proc Biol Sci. 2017 Nov 29;284(1867):
pubmed: 29142113
Nature. 1986 Mar 13-19;320(6058):172-6
pubmed: 3005879
Vision Res. 2014 Oct;103:11-9
pubmed: 25130409
Sci Rep. 2013;3:2638
pubmed: 24026421
J Physiol. 2015 Oct 1;593(19):4361-72
pubmed: 26119530
Am J Ophthalmol. 1986 Sep 15;102(3):340-5
pubmed: 3752199
Prog Retin Eye Res. 2013 Mar;33:67-84
pubmed: 23201436
Neuroscience. 2017 Dec 26;367:121-126
pubmed: 29111362
J Vis. 2009 Mar 24;9(3):17.1-16
pubmed: 19757956
Invest Ophthalmol Vis Sci. 2004 Sep;45(9):3048-54
pubmed: 15326120
Invest Ophthalmol Vis Sci. 2016 Apr;57(4):1537-46
pubmed: 27046118
Curr Biol. 2013 Apr 22;23(8):R308-9
pubmed: 23618662
IEEE Trans Neural Syst Rehabil Eng. 2011 Jun;19(3):280-9
pubmed: 21335317
Sci Rep. 2013;3:2012
pubmed: 23774670