Low-level laser therapy enhances the number of osteocytes in calvaria bone defects of ovariectomized rats.
bone
low‐level laser therapy
osteocytes
osteoporosis
Journal
Animal models and experimental medicine
ISSN: 2576-2095
Titre abrégé: Animal Model Exp Med
Pays: United States
ID NLM: 101726292
Informations de publication
Date de publication:
Mar 2019
Mar 2019
Historique:
received:
30
10
2018
revised:
18
12
2018
accepted:
09
01
2019
entrez:
25
4
2019
pubmed:
25
4
2019
medline:
25
4
2019
Statut:
epublish
Résumé
Osteoporosis can make bone repair difficult. Low-level laser therapy (LLLT) has been shown to be a promising tool for bone neoformation. This study aimed to analyze the effect of LLLT on calvaria bone defects of ovariectomized rats using stereology. Fifty-four Wistar rats were subjected to bilateral ovariectomy, and bone defects were created in calvaria after 150 days. The animals were divided into nine groups (n = 6 per group), and 24 hours after the bone defects were created they received 3, 6 or 12 sessions of LLLT at 0, 20 or 30 J/cm Data obtained showed that We conclude that LLLT stimulated bone neoformation and contributed to an increase in the total number of osteocytes, especially with a laser energy density of 30 J/cm
Sections du résumé
BACKGROUND
BACKGROUND
Osteoporosis can make bone repair difficult. Low-level laser therapy (LLLT) has been shown to be a promising tool for bone neoformation. This study aimed to analyze the effect of LLLT on calvaria bone defects of ovariectomized rats using stereology.
METHODS
METHODS
Fifty-four Wistar rats were subjected to bilateral ovariectomy, and bone defects were created in calvaria after 150 days. The animals were divided into nine groups (n = 6 per group), and 24 hours after the bone defects were created they received 3, 6 or 12 sessions of LLLT at 0, 20 or 30 J/cm
RESULTS
RESULTS
Data obtained showed that
CONCLUSION
CONCLUSIONS
We conclude that LLLT stimulated bone neoformation and contributed to an increase in the total number of osteocytes, especially with a laser energy density of 30 J/cm
Identifiants
pubmed: 31016287
doi: 10.1002/ame2.12056
pii: AME212056
pmc: PMC6431244
doi:
Types de publication
Journal Article
Langues
eng
Pagination
51-57Déclaration de conflit d'intérêts
None.
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