Emulsion Techniques for the Production of Pharmacological Nanoparticles.
bioimaging
biosensor
drug delivery
emulsion
nanoparticles
Journal
Macromolecular bioscience
ISSN: 1616-5195
Titre abrégé: Macromol Biosci
Pays: Germany
ID NLM: 101135941
Informations de publication
Date de publication:
06 2019
06 2019
Historique:
received:
24
02
2019
revised:
10
04
2019
pubmed:
25
4
2019
medline:
14
4
2020
entrez:
25
4
2019
Statut:
ppublish
Résumé
Nanoparticles have the advantages over micron-sized particles to typically provide higher intracellular uptake and drug bioavailability. Emulsion techniques are commonly used methods for producing nanoparticles aiming at high encapsulation efficiency, high stability, and low toxicity. Here, the recent developments of nanoparticles prepared from emulsions, the synthesis of nanoparticles, their physicochemical properties, and their biomedical applications are discussed. Selection of techniques, such as emulsion polymerization, miniemulsion polymerization, microemulsion polymerization, and emulsion-solvent evaporation processes, strongly influences morphologies, size distributions, and particle properties. Details in the synthetic strategies governing the performance of nanoparticles in bioimaging, biosensing, and drug delivery are presented. Benefits and limitations of molecular imaging techniques are also discussed.
Identifiants
pubmed: 31016873
doi: 10.1002/mabi.201900063
doi:
Substances chimiques
Emulsions
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
e1900063Informations de copyright
© 2019 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.