Anemia, Iron Deficiency, and Iron Supplementation in Relation to Mortality among HIV-Infected Patients Receiving Highly Active Antiretroviral Therapy in Tanzania.


Journal

The American journal of tropical medicine and hygiene
ISSN: 1476-1645
Titre abrégé: Am J Trop Med Hyg
Pays: United States
ID NLM: 0370507

Informations de publication

Date de publication:
06 2019
Historique:
pubmed: 25 4 2019
medline: 24 1 2020
entrez: 25 4 2019
Statut: ppublish

Résumé

Anemia in HIV-infected patients improves with highly active antiretroviral therapy (HAART); however, it may still be associated with mortality among patients receiving treatment. We examined the associations of anemia severity and iron deficiency anemia (IDA) at HAART initiation and during monthly prospective follow-up with mortality among 40,657 adult HIV-infected patients receiving HAART in Dar es Salaam, Tanzania. Proportional hazards models were used to examine the associations of anemia severity and IDA at HAART initiation and during follow-up with mortality. A total of 6,261 deaths were reported. Anemia severity at HAART initiation and during follow-up was associated with an increasing risk of mortality (trend tests

Identifiants

pubmed: 31017077
doi: 10.4269/ajtmh.18-0096
pmc: PMC6553903
doi:

Substances chimiques

Anti-HIV Agents 0
Iron E1UOL152H7

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

1512-1520

Subventions

Organisme : NIDDK NIH HHS
ID : P30 DK040561
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR001863
Pays : United States
Organisme : PEPFAR
Pays : United States

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Auteurs

Batool A Haider (BA)

Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts.
Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts.

Donna Spiegelman (D)

Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts.
Department of Global Health and Population, Harvard School of Public Health, Boston, Massachusetts.
Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts.
Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts.

Ellen Hertzmark (E)

Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts.

David Sando (D)

Management and Development for Health, Dar es Salaam, Tanzania.

Christopher Duggan (C)

Center for Nutrition, Boston Children's Hospital, Boston, Massachusetts.
Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts.

Abel Makubi (A)

School of Medicine, Muhimbili University of Health and Allied Sciences (MUHAS), Dar es Salaam, Tanzania.
Management and Development for Health, Dar es Salaam, Tanzania.

Christopher Sudfeld (C)

Department of Global Health and Population, Harvard School of Public Health, Boston, Massachusetts.

Eric Aris (E)

Management and Development for Health, Dar es Salaam, Tanzania.

Guerino E Chalamilla (GE)

Management and Development for Health, Dar es Salaam, Tanzania.
Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts.

Wafaie W Fawzi (WW)

Department of Global Health and Population, Harvard School of Public Health, Boston, Massachusetts.
Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts.
Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts.

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