Median Arcuate Ligament Compression in Orthotopic Liver Transplantation: Results from a Single-Center Analysis and a European Survey Study.
Dunbar syndrome
MALS
clinical outcome
median arcuate ligament syndrome
orthotopic liver transplantation
surgical complications
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
23 Apr 2019
23 Apr 2019
Historique:
received:
21
03
2019
revised:
15
04
2019
accepted:
22
04
2019
entrez:
26
4
2019
pubmed:
26
4
2019
medline:
26
4
2019
Statut:
epublish
Résumé
Median arcuate ligament compression (MALC) potentially causes arterial complications in orthotopic liver transplantation (OLT). Here we aimed to investigate the incidence of MALC and its impact on clinical outcome after OLT. In addition, we performed an international survey among 52 European liver transplant centers to explore local protocols on the management of these patients. Data of 286 consecutive OLT recipients from a prospective database were analyzed retrospectively (05/2010-07/2017). Preoperative computed-tomography images were evaluated. Celiac axis stenosis due to MALC was found in 34 patients (12%). Intrinsic stenosis was present in 16 (6%) patients. Twenty-six patients (77%) with MALC underwent standard arterial revascularization with median arcuate ligament (MAL)-division. Patients treated for MALC had comparable baseline data and no difference was found in early- and long-term outcome compared to the rest of our cohort. Our survey found heterogeneous strategies regarding diagnosis and treatment of MALC. Only 29% of the centers reported the division of MAL in these patients as routine procedure. Even though there is no consensus on diagnosis and management of MALC among European centers, a surgical division of MAL is feasible and safe and should be considered in OLT recipients with MALC.
Identifiants
pubmed: 31018577
pii: jcm8040550
doi: 10.3390/jcm8040550
pmc: PMC6518097
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : START-Program
ID : #136/17
Organisme : START-Program
ID : #23/19
Organisme : Excellence Initiative of the German federal and state governments
ID : G:(DE-82) ZUK2-SF-OPSF443
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