Ceritinib-related interstitial lung disease improving after treatment cessation without recurrence under either crizotinib or brigatinib: a case report.
Anaplastic lymphoma kinase rearrangement (ALK rearrangement)
ceritinib
diffuse interstitial pneumonitis
non-small cell lung cancer (NSCLC)
Journal
Annals of translational medicine
ISSN: 2305-5839
Titre abrégé: Ann Transl Med
Pays: China
ID NLM: 101617978
Informations de publication
Date de publication:
Mar 2019
Mar 2019
Historique:
entrez:
26
4
2019
pubmed:
26
4
2019
medline:
26
4
2019
Statut:
ppublish
Résumé
Anaplastic lymphoma kinase inhibitors (ALKi) like ceritinib are considered standard for front-line treatment of non-small cell lung cancers (NSCLC) harboring a translocation of the anaplastic lymphoma kinase (ALK) gene. We report herein a case of interstitial lung disease (ILD) that developed following a 7-month ceritinib treatment without recurrence under either crizotinib or brigatinib, two others ALKi.
Identifiants
pubmed: 31019956
doi: 10.21037/atm.2019.01.24
pii: atm-07-05-106
pmc: PMC6462648
doi:
Types de publication
Case Reports
Langues
eng
Pagination
106Déclaration de conflit d'intérêts
Conflicts of Interest: B Mennecier and E Quoix were investigators of clinical trials regarding crizotinib, ceritinib, brigatinib and lorlatinib. The other authors have no conflicts of interest to declare.
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