The effects of vitamins and selenium mixture against brain tissue induced by d-galactosamine.
antioxidant
brain
enzymes
galactosamine
oxidative stress
Journal
Journal of biochemical and molecular toxicology
ISSN: 1099-0461
Titre abrégé: J Biochem Mol Toxicol
Pays: United States
ID NLM: 9717231
Informations de publication
Date de publication:
Aug 2019
Aug 2019
Historique:
received:
21
11
2018
revised:
18
01
2019
accepted:
08
04
2019
pubmed:
26
4
2019
medline:
14
1
2020
entrez:
26
4
2019
Statut:
ppublish
Résumé
Brain damage is a major complication of fulminant hepatic failure. d-Galactosamine (d-GalN)-induced liver toxicity causes damage to brain. The effects of vitamins and selenium mixture against d-GalN stimulated brain injury were investigated in this study. Sprague-Dawley female rats aged 2.0-2.5 months were used for the study. The rats were divided into four categories. A 0.9% NaCl solution was intraperitoneally given to the experimental rats in the first group. Using gavage technique, the second group of animals were subjected to a formulation consisting of 100 mg·kg
Substances chimiques
beta Carotene
01YAE03M7J
Galactosamine
7535-00-4
alpha-Tocopherol
H4N855PNZ1
Selenium
H6241UJ22B
Ascorbic Acid
PQ6CK8PD0R
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e22347Informations de copyright
© 2019 Wiley Periodicals, Inc.