Strategic Planning for Tuberculosis Control in the Republic of Fiji.
disease modelling
epidemiology
health policy
public health
simulation
tuberculosis
Journal
Tropical medicine and infectious disease
ISSN: 2414-6366
Titre abrégé: Trop Med Infect Dis
Pays: Switzerland
ID NLM: 101709042
Informations de publication
Date de publication:
24 Apr 2019
24 Apr 2019
Historique:
received:
20
02
2019
revised:
17
04
2019
accepted:
22
04
2019
entrez:
27
4
2019
pubmed:
27
4
2019
medline:
27
4
2019
Statut:
epublish
Résumé
The tuberculosis (TB) health burden in Fiji has been declining in recent years, although challenges remain in improving control of the diabetes co-epidemic and achieving adequate case detection across the widely dispersed archipelago. We applied a mathematical model of TB transmission to the TB epidemic in Fiji that captured the historical reality over several decades, including age stratification, diabetes, varying disease manifestations, and incorrect diagnoses. Next, we simulated six intervention scenarios that are under consideration by the Fiji National Tuberculosis Program. Our findings show that the interventions were able to achieve only modest improvements in disease burden, with awareness raising being the most effective intervention to reduce TB incidence, and treatment support yielding the highest impact on mortality. These improvements would fall far short of the ambitious targets that have been set by the country, and could easily be derailed by moderate increases in the diabetes burden. Furthermore, the effectiveness of the interventions was limited by the extensive pool of latent TB infection, because the programs were directed at only active cases, and thus were unlikely to achieve the desired reductions in burden. Therefore, it is essential to address the co-epidemic of diabetes and treat people with latent TB infection.
Identifiants
pubmed: 31022901
pii: tropicalmed4020071
doi: 10.3390/tropicalmed4020071
pmc: PMC6631049
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Global Fund to Fight AIDS, Tuberculosis and Malaria
ID : !!!!
Déclaration de conflit d'intérêts
The authors declare no conflict of interest. The funders had no role in the design, execution, interpretation, or writing of the study.
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