Research Gaps in Primary Pediatric Hypertension.


Journal

Pediatrics
ISSN: 1098-4275
Titre abrégé: Pediatrics
Pays: United States
ID NLM: 0376422

Informations de publication

Date de publication:
05 2019
Historique:
accepted: 11 02 2019
pubmed: 27 4 2019
medline: 15 11 2019
entrez: 27 4 2019
Statut: ppublish

Résumé

Hypertension affects >40% of the US population and is a major contributor to cardiovascular-related morbidity and mortality. Although less common among children and adolescents, hypertension affects 1% to 5% of all youth. The 2017 Clinical Practice Guideline for the Diagnosis and Management of High Blood Pressure in Children and Adolescents provided updates and strategies regarding the diagnosis and management of hypertension in youth. Despite this important information, many gaps in knowledge remain, such as the etiology, prevalence, and trends of hypertension; the utility and practicality of ambulatory blood pressure monitoring; practical goals for lifestyle modification that are generalizable; the long-term end-organ impacts of hypertension in youth; and the long-term safety and efficacy of antihypertensive therapy in youth. The

Identifiants

pubmed: 31023830
pii: peds.2018-3517
doi: 10.1542/peds.2018-3517
pmc: PMC6564054
pii:
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Review

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2019 by the American Academy of Pediatrics.

Déclaration de conflit d'intérêts

POTENTIAL CONFLICT OF INTEREST: Dr Baker-Smith was the methodologist and epidemiologist for the 2017 Clinical Practice Guideline for the Diagnosis and Management of High Blood Pressure in Children and Adolescents; Dr Daniels has served as a consultant for Sanofi and is the chair of a data monitoring and safety committee for Novo Nordisk; the other authors have indicated they have no potential conflicts of interest to disclose.

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Auteurs

Perdita Taylor-Zapata (P)

Obstetric and Pediatric Pharmacology and Therapeutics Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, taylorpe@mail.nih.gov.

Carissa M Baker-Smith (CM)

School of Medicine, University of Maryland, Baltimore, Maryland.

Gilbert Burckart (G)

Office of Clinical Pharmacology, Immediate Office of the Commissioner, and.

Stephen R Daniels (SR)

Department of Pediatrics, Section of Cardiology, School of Medicine, University of Colorado, Aurora, Colorado.

Joseph T Flynn (JT)

School of Medicine, University of Washington, Seattle, Washington.

George Giacoia (G)

Obstetric and Pediatric Pharmacology and Therapeutics Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development.

Dionna Green (D)

Office of Clinical Pharmacology, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland.

Aaron S Kelly (AS)

Department of Pediatrics, Center for Pediatric Obesity Medicine, University of Minnesota, Minneapolis, Minnesota.

Mona Khurana (M)

Division of Pediatric and Maternal Health, Office of New Drugs.

Jennifer S Li (JS)

Department of Pediatrics, Duke University, Durham, North Carolina; and.

Charlotte Pratt (C)

Clinical Applications and Prevention Branch, National Heart, Lung, and Blood Institute, and.

Elaine M Urbina (EM)

Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.

Anne Zajicek (A)

Office of Clinical Research Training and Medical Education, National Institutes of Health, Bethesda, Maryland.

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