Spontaneous Cingulate High-Current Spikes Signal Normal and Pathological Pain States.


Journal

The Journal of neuroscience : the official journal of the Society for Neuroscience
ISSN: 1529-2401
Titre abrégé: J Neurosci
Pays: United States
ID NLM: 8102140

Informations de publication

Date de publication:
26 06 2019
Historique:
received: 08 10 2018
revised: 08 04 2019
accepted: 15 04 2019
pubmed: 27 4 2019
medline: 19 6 2020
entrez: 27 4 2019
Statut: ppublish

Résumé

Prominent 7-12 Hz oscillations in frontal cortical networks in rats have been reported. However, the mechanism of generation and the physiological function of this brain rhythm have not yet been clarified. Multichannel extracellular field potentials of the ACC were recorded and analyzed using the current source density method in halothane-anesthetized rats. Spontaneous high-current spikes (HCSs) were localized in the deep part of layer II/III and upper part of layer V of the ACC. The frequency of HCSs in the ACC was 7-12 Hz, with an amplitude of 6.5 ± 0.76 mV/mm

Identifiants

pubmed: 31023834
pii: JNEUROSCI.2590-18.2019
doi: 10.1523/JNEUROSCI.2590-18.2019
pmc: PMC6595960
doi:

Substances chimiques

Analgesics, Opioid 0
Morphine 76I7G6D29C

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

5128-5142

Informations de copyright

Copyright © 2019 the authors.

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Auteurs

Hsi-Chien Shih (HC)

Institute of Biomedical Sciences, Academia Sinica, Taipei, 11529, Taiwan, Republic of China.

Jenq-Wei Yang (JW)

Institute of Physiology, University Medical Center of the Johannes Gutenberg, University Mainz, D-55128 Mainz, Germany.
Laboratory of Neural Circuit Assembly, Brain Research Institute, University of Zurich, CH-8057 Zurich, Switzerland, and.

Chia-Ming Lee (CM)

Research Center for Applied Sciences, Academia Sinica, Taipei, 11529, Taiwan, Republic of China.

Bai-Chuang Shyu (BC)

Institute of Biomedical Sciences, Academia Sinica, Taipei, 11529, Taiwan, Republic of China, bmbai@gate.sinica.edu.tw.

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Classifications MeSH