STIM1 Is Required for Remodeling of the Endoplasmic Reticulum and Microtubule Cytoskeleton in Steering Growth Cones.
Animals
Axon Guidance
/ physiology
Calcium
/ metabolism
Cytoskeleton
/ genetics
Endoplasmic Reticulum
/ metabolism
Growth Cones
/ metabolism
Microtubule-Associated Proteins
/ genetics
Microtubules
/ genetics
Motor Neurons
/ metabolism
Pseudopodia
/ metabolism
Rats
Sensory Receptor Cells
/ metabolism
Stromal Interaction Molecule 1
/ genetics
Zebrafish
STIM1
axon guidance
calcium
endoplasmic reticulum
microtubule
optogenetic
Journal
The Journal of neuroscience : the official journal of the Society for Neuroscience
ISSN: 1529-2401
Titre abrégé: J Neurosci
Pays: United States
ID NLM: 8102140
Informations de publication
Date de publication:
26 06 2019
26 06 2019
Historique:
received:
27
09
2018
revised:
03
04
2019
accepted:
04
04
2019
pubmed:
27
4
2019
medline:
19
6
2020
entrez:
27
4
2019
Statut:
ppublish
Résumé
The spatial and temporal regulation of calcium signaling in neuronal growth cones is essential for axon guidance. In growth cones, the endoplasmic reticulum (ER) is a significant source of calcium signals. However, it is not clear whether the ER is remodeled during motile events to localize calcium signals in steering growth cones. The expression of the ER-calcium sensor, stromal interacting molecule 1 (STIM1) is necessary for growth cone steering toward the calcium-dependent guidance cue BDNF, with STIM1 functioning to sustain calcium signals through store-operated calcium entry. However, STIM1 is also required for growth cone steering away from semaphorin-3a, a guidance cue that does not activate ER-calcium release, suggesting multiple functions of STIM1 within growth cones (Mitchell et al., 2012). STIM1 also interacts with microtubule plus-end binding proteins EB1/EB3 (Grigoriev et al., 2008). Here, we show that STIM1 associates with EB1/EB3 in growth cones and that STIM1 expression is critical for microtubule recruitment and subsequent ER remodeling to the motile side of steering growth cones. Furthermore, we extend our data
Identifiants
pubmed: 31023836
pii: JNEUROSCI.2496-18.2019
doi: 10.1523/JNEUROSCI.2496-18.2019
pmc: PMC6595949
doi:
Substances chimiques
EB1 microtubule binding proteins
0
Microtubule-Associated Proteins
0
Stromal Interaction Molecule 1
0
Calcium
SY7Q814VUP
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
5095-5114Informations de copyright
Copyright © 2019 the authors.
Références
J Neurosci. 1999 May 15;19(10):3860-73
pubmed: 10234018
Neuron. 1999 May;23(1):139-48
pubmed: 10402200
J Neurobiol. 1999 Nov 5;41(2):230-41
pubmed: 10512980
J Neurosci. 1999 Oct 15;19(20):8894-908
pubmed: 10516309
Nature. 2000 Jan 6;403(6765):89-93
pubmed: 10638759
Nature. 2000 Jan 6;403(6765):93-8
pubmed: 10638760
J Neurosci. 2000 Feb 1;20(3):1044-55
pubmed: 10648710
Neuron. 1999 Sep;24(1):261-73
pubmed: 10677043
Development. 2000 May;127(9):1953-60
pubmed: 10751183
Development. 2000 Jun;127(12):2653-62
pubmed: 10821763
J Neurobiol. 2000 Aug;44(2):174-83
pubmed: 10934320
Science. 2001 Mar 9;291(5510):1983-7
pubmed: 11239161
Trends Neurosci. 2001 May;24(5):271-6
pubmed: 11311379
J Neurosci. 2002 Nov 1;22(21):9358-67
pubmed: 12417661
Dev Biol. 2002 Dec 15;252(2):241-56
pubmed: 12482713
Methods Cell Sci. 2001;23(4):205-9
pubmed: 12486331
J Neurosci. 2003 Apr 1;23(7):2655-64
pubmed: 12684451
Neuron. 2004 Jun 24;42(6):897-912
pubmed: 15207235
Neuron. 2004 Sep 16;43(6):835-46
pubmed: 15363394
Nature. 2005 Apr 14;434(7035):898-904
pubmed: 15758951
Nature. 2005 Apr 14;434(7035):894-8
pubmed: 15758952
J Cell Biol. 2005 May 9;169(3):435-45
pubmed: 15866891
Curr Biol. 2005 Jul 12;15(13):1235-41
pubmed: 16005298
J Cell Biol. 2005 Sep 26;170(7):1159-67
pubmed: 16172206
J Cell Sci. 2006 Mar 1;119(Pt 5):951-7
pubmed: 16495486
Nature. 2006 May 11;441(7090):179-85
pubmed: 16582901
Neuron. 2006 Jun 1;50(5):683-95
pubmed: 16731508
Nat Cell Biol. 2006 Sep;8(9):1003-10
pubmed: 16906149
J Cell Biol. 2006 Sep 11;174(6):815-25
pubmed: 16966423
J Neurosci. 2006 Nov 22;26(47):12127-36
pubmed: 17122037
Nat Neurosci. 2007 Jan;10(1):58-66
pubmed: 17159991
Nat Methods. 2007 Apr;4(4):323-6
pubmed: 17369834
Dev Dyn. 2007 Nov;236(11):3088-99
pubmed: 17937395
J Neurosci Res. 1991 Sep;30(1):242-58
pubmed: 1795407
Curr Biol. 2008 Feb 12;18(3):177-82
pubmed: 18249114
Nat Rev Mol Cell Biol. 2008 Apr;9(4):309-22
pubmed: 18322465
Nat Neurosci. 2008 Jul;11(7):762-71
pubmed: 18536712
Neuron. 2008 Jun 12;58(5):694-707
pubmed: 18549782
Nat Cell Biol. 2008 Oct;10(10):1181-9
pubmed: 18806788
Nat Cell Biol. 2009 Apr;11(4):433-42
pubmed: 19287379
Zebrafish. 2009 Mar;6(1):69-77
pubmed: 19374550
Mol Biol Cell. 2009 Aug;20(16):3700-12
pubmed: 19570918
Cell. 2009 Jul 23;138(2):366-76
pubmed: 19632184
Neural Dev. 2009 Aug 03;4:29
pubmed: 19650914
Nature. 2009 Sep 17;461(7262):407-10
pubmed: 19759620
Front Neural Circuits. 2009 Oct 09;3:13
pubmed: 19862330
J Neurosci. 1991 Feb;11(2):311-7
pubmed: 1992002
J Cell Biol. 1991 Apr;113(2):347-59
pubmed: 2010466
Am J Physiol Cell Physiol. 2010 May;298(5):C993-1005
pubmed: 20107038
Science. 2010 Jan 29;327(5965):547-52
pubmed: 20110498
Nature. 2010 Feb 11;463(7282):823-7
pubmed: 20148037
Traffic. 2011 Jan;12(1):28-41
pubmed: 20955502
Cell Signal. 2011 Feb;23(2):497-505
pubmed: 21062642
Nat Rev Neurosci. 2011 Apr;12(4):191-203
pubmed: 21386859
Proc Natl Acad Sci U S A. 2011 Aug 16;108(33):13776-81
pubmed: 21795610
Chem Biol. 2011 Jul 29;18(7):880-90
pubmed: 21802009
Dev Biol. 2012 May 1;365(1):290-302
pubmed: 22426004
Annu Rev Neurosci. 2012;35:25-47
pubmed: 22540978
J Cell Mol Med. 2012 Nov;16(11):2715-25
pubmed: 22681560
J Neurochem. 2012 Sep;122(6):1155-66
pubmed: 22712562
Proc Natl Acad Sci U S A. 2013 Jan 22;110(4):1524-9
pubmed: 23302694
PLoS One. 2013;8(3):e57539
pubmed: 23469201
Proc Natl Acad Sci U S A. 2013 Mar 26;110(13):5091-6
pubmed: 23479643
Front Neural Circuits. 2013 Apr 01;7:53
pubmed: 23554587
J Biol Chem. 2013 Jul 19;288(29):20837-42
pubmed: 23775074
Cell Calcium. 2013 Sep;54(3):246-56
pubmed: 23871111
J Neurosci. 2013 Oct 16;33(42):16471-82
pubmed: 24133252
Mol Brain. 2013 Dec 01;6:51
pubmed: 24289807
Nat Cell Biol. 2014 Feb;16(2):133-44
pubmed: 24463606
Biochim Biophys Acta. 2015 Jan;1853(1):233-43
pubmed: 25447552
Neuron. 1989 Jan;2(1):1097-104
pubmed: 2624743
Nat Biotechnol. 2015 Oct;33(10):1092-6
pubmed: 26368050
Transl Psychiatry. 2015 Sep 22;5:e643
pubmed: 26393489
Curr Biol. 2016 Mar 21;26(6):743-54
pubmed: 26923787
J Neurosci. 2016 May 18;36(20):5636-49
pubmed: 27194341
Trends Cell Biol. 2016 Dec;26(12):934-943
pubmed: 27339937
Zebrafish. 2017 Feb;14(1):69-72
pubmed: 27631880
Sci Rep. 2017 Feb 01;7:40740
pubmed: 28145469
Neuron. 2017 Feb 22;93(4):867-881.e6
pubmed: 28162809
Dev Neurobiol. 2017 Sep;77(9):1101-1113
pubmed: 28371371
Proc Natl Acad Sci U S A. 2017 Jun 13;114(24):E4859-E4867
pubmed: 28559323
J Cell Biol. 2018 Jun 4;217(6):2047-2058
pubmed: 29563214
J Neurosci. 1987 Nov;7(11):3588-99
pubmed: 3681406
J Neurosci. 1986 Aug;6(8):2278-89
pubmed: 3746410
J Neurosci. 1985 Sep;5(9):2345-58
pubmed: 4032000
Proc Natl Acad Sci U S A. 1994 Aug 2;91(16):7510-4
pubmed: 7519781
Nature. 1995 Jun 29;375(6534):784-7
pubmed: 7596410
J Cell Biol. 1995 Jan;128(1-2):127-37
pubmed: 7822410
J Neurosci. 1994 Oct;14(10):5959-72
pubmed: 7931556
Neuron. 1993 Aug;11(2):237-51
pubmed: 8352941
Nature. 1993 Feb 25;361(6414):721-4
pubmed: 8441465
Proc Natl Acad Sci U S A. 1996 Dec 24;93(26):15221-6
pubmed: 8986791
J Neurobiol. 1996 Sep;31(1):1-15
pubmed: 9120430
Nature. 1997 Jul 17;388(6639):275-9
pubmed: 9230436
Neuron. 1997 Dec;19(6):1225-35
pubmed: 9427246
J Neurosci. 1998 Jul 15;18(14):5403-14
pubmed: 9651222
Curr Biol. 1998 Jul 2;8(14):798-806
pubmed: 9663388
Science. 1998 Sep 4;281(5382):1515-8
pubmed: 9727979
J Neurobiol. 1998 Dec;37(4):622-32
pubmed: 9858263
Nature. 1999 Jan 28;397(6717):350-5
pubmed: 9950427