N
AML
METTL14
METTL3
RNA
epitranscriptomics
leukemia
m6A
Journal
Frontiers in oncology
ISSN: 2234-943X
Titre abrégé: Front Oncol
Pays: Switzerland
ID NLM: 101568867
Informations de publication
Date de publication:
2019
2019
Historique:
received:
10
01
2019
accepted:
19
03
2019
entrez:
27
4
2019
pubmed:
27
4
2019
medline:
27
4
2019
Statut:
epublish
Résumé
Recent studies have uncovered an important role for RNA modifications in gene expression regulation, which led to the birth of the epitranscriptomics field. It is now acknowledged that RNA modifiers play a crucial role in the control of differentiation of stem and progenitor cells and that changes in their levels are a relevant feature of different types of cancer. To date, among more than 160 different RNA chemical modifications, the more relevant in cancer biology is the reversible and dynamic N
Identifiants
pubmed: 31024852
doi: 10.3389/fonc.2019.00251
pmc: PMC6465620
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
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