Effectiveness of topical Nigella sativa for vitiligo treatment.


Journal

Dermatologic therapy
ISSN: 1529-8019
Titre abrégé: Dermatol Ther
Pays: United States
ID NLM: 9700070

Informations de publication

Date de publication:
07 2019
Historique:
received: 04 03 2019
revised: 22 04 2019
accepted: 23 04 2019
pubmed: 27 4 2019
medline: 20 2 2020
entrez: 27 4 2019
Statut: ppublish

Résumé

Vitiligo is a pigment disease characterized by the disruption of melanocyte structure and function. Its etiology is unknown; however, genetic predisposition, biochemical factors, and neural mechanisms are thought to be effective. Although many agents are being used for its treatment, generally there is no absolute cure. The aim of the present study is to evaluate the effectiveness of topical Nigella sativa seed oil on vitiligo patients. Thirty-three vitiligo patients were included in the study. Totally 47 areas were evaluated in all patients. Cream containing N sativa seed oil was topically applied to hands, face, and genital region two times a day for 6 months. Statistically significant repigmentation was detected in hands, face, and genital region, the three treatment areas, and the p values are found .005, .001, and .004, respectively. N sativa can be used as an adjuvant therapy that can contribute to the treatment especially in sensitive skin areas like genital region.

Identifiants

pubmed: 31025474
doi: 10.1111/dth.12949
doi:

Substances chimiques

Dermatologic Agents 0
Plant Oils 0
caraway oil C2J9B08Q3I

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e12949

Informations de copyright

© 2019 Wiley Periodicals, Inc.

Auteurs

Gulbahar Sarac (G)

Department of Dermatology, İnönü University Faculty of Medicine, Malatya, Turkey.

Yelda Kapicioglu (Y)

Department of Dermatology, Liv Hospital, Istanbul, Turkey.

Serpil Sener (S)

Department of Dermatology, İnönü University Faculty of Medicine, Malatya, Turkey.

Irem Mantar (I)

Department of Dermatology, İnönü University Faculty of Medicine, Malatya, Turkey.

Saim Yologlu (S)

Department of Biostatistics, İnönü University Faculty of Medicine, Malatya, Turkey.

Cihat Dundar (C)

Biota Laboratories, R&D Center, Istanbul, Turkey.

Murat Turkoglu (M)

Biota Laboratories, R&D Center, Istanbul, Turkey.

Erkin Pekmezci (E)

Department of Dermatology, Gozde Hospital, Malatya, Turkey.

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Classifications MeSH