Vessel Wall Imaging After Subarachnoid Hemorrhage in Patients with Multiple Intracranial Aneurysms: A Cautionary Case.


Journal

World neurosurgery
ISSN: 1878-8769
Titre abrégé: World Neurosurg
Pays: United States
ID NLM: 101528275

Informations de publication

Date de publication:
Jul 2019
Historique:
received: 14 12 2018
revised: 14 04 2019
accepted: 15 04 2019
pubmed: 27 4 2019
medline: 16 1 2020
entrez: 27 4 2019
Statut: ppublish

Résumé

Almost 30% of patients with subarachnoid hemorrhage (SAH) are found to have multiple aneurysms. This can potentially present a serious management dilemma when planning treatment. Magnetic resonance imaging vessel wall imaging (VWI) has been proposed as a reliable technique in differentiating between ruptured and unruptured aneurysms in patients with multiple intracranial aneurysms who present with SAH. Expert consensus now supports this as a possible use for the technique. Here we present a patient presenting a particular clinical dilemma with SAH and a left third nerve palsy and transient speech disturbance who had circumferential enhancement in the left larger 3.5-mm irregular middle cerebral artery aneurysm and no detectable enhancement in what was angiographically either a 1.5-mm smooth noncompressive left posterior communicating artery aneurysm or infundibulum, but was proved at surgery to be the culprit aneurysm. Although a case of concurrent false positive and false negative in the same patient has not previously been reported, the positive predictive value of VWI for rupture status is known to be much lower than its negative predictive value, and a case like this might be expected to occur in 0.6% of patients. Therefore, whereas VWI is a valuable tool, it should be used in conjunction with, and not in lieu of, traditional indicators of aneurysm rupture.

Sections du résumé

BACKGROUND BACKGROUND
Almost 30% of patients with subarachnoid hemorrhage (SAH) are found to have multiple aneurysms. This can potentially present a serious management dilemma when planning treatment. Magnetic resonance imaging vessel wall imaging (VWI) has been proposed as a reliable technique in differentiating between ruptured and unruptured aneurysms in patients with multiple intracranial aneurysms who present with SAH. Expert consensus now supports this as a possible use for the technique.
CASE DESCRIPTION METHODS
Here we present a patient presenting a particular clinical dilemma with SAH and a left third nerve palsy and transient speech disturbance who had circumferential enhancement in the left larger 3.5-mm irregular middle cerebral artery aneurysm and no detectable enhancement in what was angiographically either a 1.5-mm smooth noncompressive left posterior communicating artery aneurysm or infundibulum, but was proved at surgery to be the culprit aneurysm.
CONCLUSION CONCLUSIONS
Although a case of concurrent false positive and false negative in the same patient has not previously been reported, the positive predictive value of VWI for rupture status is known to be much lower than its negative predictive value, and a case like this might be expected to occur in 0.6% of patients. Therefore, whereas VWI is a valuable tool, it should be used in conjunction with, and not in lieu of, traditional indicators of aneurysm rupture.

Identifiants

pubmed: 31026656
pii: S1878-8750(19)31124-6
doi: 10.1016/j.wneu.2019.04.130
pii:
doi:

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

414-417

Informations de copyright

Copyright © 2019 Elsevier Inc. All rights reserved.

Auteurs

Ardalan Zolnourian (A)

Department of Neurosurgery, Wessex Neurological Centre, Southampton, Hampshire, United Kingdom. Electronic address: a.zolnourian@soton.ac.uk.

Nicholas Borg (N)

Department of Neurosurgery, Wessex Neurological Centre, Southampton, Hampshire, United Kingdom.

Taiwo Akhigbe (T)

Department of Neurosurgery, Wessex Neurological Centre, Southampton, Hampshire, United Kingdom.

Jason Macdonald (J)

Department of Neuroradiology, Wessex Neurological Centre, Southampton, Hampshire, United Kingdom.

Diederik Bulters (D)

Department of Neurosurgery, Wessex Neurological Centre, Southampton, Hampshire, United Kingdom.

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Classifications MeSH