Rapid detection of non-volatile household pesticides in drained gastric juice by ambient mass spectrometry for emergency management.

Adult Emergency Medical Services Female Gastric Juice / chemistry Humans Male Middle Aged Pesticides / analysis Point-of-Care Systems Spectrometry, Mass, Electrospray Ionization
Ambient mass spectrometry Emergency management Gastric juice Household pesticides Point-of-care

Journal

Analytica chimica acta
ISSN: 1873-4324
Titre abrégé: Anal Chim Acta
Pays: Netherlands
ID NLM: 0370534

Informations de publication

Date de publication:
20 Aug 2019
Historique:
received: 06 12 2018
revised: 06 03 2019
accepted: 07 03 2019
entrez: 28 4 2019
pubmed: 28 4 2019
medline: 2 7 2019
Statut: ppublish

Résumé

In order to provide timely emergency management for the patients accidently or intentionally ingested of household pesticides, it is crucial to develop a point-of-care analytical technique for early ex vivo identification of swallowed pesticides. In this study, probe sampling combined with electrospray laser desorption ionization/mass spectrometry (ELDI/MS) was performed to rapidly detect spiked non-volatile household pesticides in the gastric juice drained from the patients during lavage. Since no sample pretreatment is required, probe sampling is fast, and high thermal energy for analyte desorption is provided; ELDI/MS detects the household pesticides in gastric juice within 30 s. The detection limits of the household pesticides were found to be 0.05-1 mg/L, this makes ELDI/MS combined with probe sampling a novel and efficient analytical tool for providing important toxicological information to ensure an appropriate emergency medical response.

Identifiants

DOI: 10.1016/j.aca.2019.03.013 PMID: 31027536
pubmed: 31027536
pii: S0003-2670(19)30286-7
doi: 10.1016/j.aca.2019.03.013
pii:
doi:

Substances chimiques

Pesticides 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

69-78

Informations de copyright

Copyright © 2019. Published by Elsevier B.V.

Auteurs

Hung Su (H)

Department of Chemistry, National Sun Yat-Sen University, Kaohsiung, Taiwan.

Yen-Ping Lin (YP)

Department of Chemistry, National Sun Yat-Sen University, Kaohsiung, Taiwan.

Shih-Chia Yang (SC)

Department of Emergency Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.

Chao-Hung Kuo (CH)

Division of Gastroenterology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan; Center for Stem Cell Research, Kaohsiung Medical University, Kaohsiung, Taiwan.

Deng-Chyang Wu (DC)

Division of Gastroenterology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan; Center for Stem Cell Research, Kaohsiung Medical University, Kaohsiung, Taiwan.

Jentaie Shiea (J)

Department of Chemistry, National Sun Yat-Sen University, Kaohsiung, Taiwan; Center for Stem Cell Research, Kaohsiung Medical University, Kaohsiung, Taiwan; Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung, Taiwan; Research Center for Environmental Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.

Chi-Wei Lee (CW)

Institute of Medical Science and Technology, National Sun Yat-Sen University, Kaohsiung, Taiwan; Research Center for Environmental Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. Electronic address: chiweilee1964@gmail.com.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Rapid detection of non-volatile household...
questionsmedicales.fr › Établissements, main d'oeuvre et services de soins de santé › Services de santé › Services des urgences médicales › Rapid detection of non-volatile household...
questionsmedicales.fr › Liquides et sécrétions biologiques › Sécrétions corporelles › Suc gastrique › Rapid detection of non-volatile household...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Rapid detection of non-volatile household...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Adulte d'âge moyen › Rapid detection of non-volatile household...
questionsmedicales.fr › Actions chimiques et utilisations › Actions toxiques › Pesticides › Rapid detection of non-volatile household...
questionsmedicales.fr › Administration des services de santé › Gestion des soins aux patients › Systèmes automatisés lit malade › Rapid detection of non-volatile household...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Spectrométrie de masse › Spectrométrie de masse ESI › Rapid detection of non-volatile household...