Assessing in vitro dermal absorption of dry residues of agrochemical sprays using human skin within OECD TG 428.
Agrochemicals
DFR
Dermal absorption
Dermal exposure
Dislodgeable foliar residues
Human skin
In vitro
Pesticides
Plant protection products
Re-entry worker risk assessment
Journal
Regulatory toxicology and pharmacology : RTP
ISSN: 1096-0295
Titre abrégé: Regul Toxicol Pharmacol
Pays: Netherlands
ID NLM: 8214983
Informations de publication
Date de publication:
Aug 2019
Aug 2019
Historique:
received:
21
12
2018
revised:
19
04
2019
accepted:
21
04
2019
pubmed:
28
4
2019
medline:
14
2
2020
entrez:
28
4
2019
Statut:
ppublish
Résumé
We describe a novel experimental method that mimics exposure to dried agrochemical residues on contact surfaces during re-entry into crops. It includes the creation of dry dislodgeable residues and subsequent transfer to human skin for in vitro measurement of dermal absorption within a standard Organisation for Economic Co-operation and Development test guideline (OECD TG) 428 study. A pre-determined volume of spray containing
Identifiants
pubmed: 31028797
pii: S0273-2300(19)30115-1
doi: 10.1016/j.yrtph.2019.04.016
pii:
doi:
Substances chimiques
Agrochemicals
0
Pesticide Residues
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
55-67Informations de copyright
Copyright © 2019 The Authors. Published by Elsevier Inc. All rights reserved.