An interdisciplinary approach to inhospital stroke improves stroke detection and treatment time.


Journal

Journal of neurointerventional surgery
ISSN: 1759-8486
Titre abrégé: J Neurointerv Surg
Pays: England
ID NLM: 101517079

Informations de publication

Date de publication:
Nov 2019
Historique:
received: 28 02 2019
revised: 31 03 2019
accepted: 02 04 2019
pubmed: 29 4 2019
medline: 1 1 2020
entrez: 29 4 2019
Statut: ppublish

Résumé

Inhospital stroke (IHS) is associated with high morbidity and mortality, likely related to multiple factors, including delayed time to recognition, associated comorbidities, and initial care from non-stroke trained providers. We hypothesized that guided revision of a formalized 'stroke code' system can improve diagnosis and time to thrombolysis and thrombectomy. IHS activations occurring at a comprehensive stroke center between 2013 and 2016 were retrospectively analyzed to guide revisions of an established stroke code protocol to improve provider communication and time to imaging, reduce stroke mimic rate, and improve the use of parallel processing. After protocol implementation, we prospectively collected data between 2016 and 2017 for comparison with the pre-implementation group, including diagnostic accuracy and relevant time points (code call to examination, examination to imaging, and imaging to intervention). We report descriptive statistics for comparison of patient characteristics and time metrics (time to imaging and reperfusion after IHS activation). Multivariable regression analysis was performed to identify independent predictors of stroke mimics and time metrics. There were 136 cases in the pre-implementation group and 69 in the post-implementation group. A reduction in stroke mimics (52% vs 33%, P=0.01) occurred after protocol initiation. Mean time to imaging after stroke code call was 7.6 min shorter (P=0.026) and mean time from imaging to acute reperfusion therapy was 45.7 vs 19.8 min (P=0.05) in the pre- versus the post-implementation group. Revision of an existing IHS protocol was associated with a lower rate of stroke mimics, and a shorter time to intravenous and intra-arterial intervention.

Sections du résumé

BACKGROUND BACKGROUND
Inhospital stroke (IHS) is associated with high morbidity and mortality, likely related to multiple factors, including delayed time to recognition, associated comorbidities, and initial care from non-stroke trained providers. We hypothesized that guided revision of a formalized 'stroke code' system can improve diagnosis and time to thrombolysis and thrombectomy.
METHODS METHODS
IHS activations occurring at a comprehensive stroke center between 2013 and 2016 were retrospectively analyzed to guide revisions of an established stroke code protocol to improve provider communication and time to imaging, reduce stroke mimic rate, and improve the use of parallel processing. After protocol implementation, we prospectively collected data between 2016 and 2017 for comparison with the pre-implementation group, including diagnostic accuracy and relevant time points (code call to examination, examination to imaging, and imaging to intervention). We report descriptive statistics for comparison of patient characteristics and time metrics (time to imaging and reperfusion after IHS activation). Multivariable regression analysis was performed to identify independent predictors of stroke mimics and time metrics.
RESULTS RESULTS
There were 136 cases in the pre-implementation group and 69 in the post-implementation group. A reduction in stroke mimics (52% vs 33%, P=0.01) occurred after protocol initiation. Mean time to imaging after stroke code call was 7.6 min shorter (P=0.026) and mean time from imaging to acute reperfusion therapy was 45.7 vs 19.8 min (P=0.05) in the pre- versus the post-implementation group.
CONCLUSION CONCLUSIONS
Revision of an existing IHS protocol was associated with a lower rate of stroke mimics, and a shorter time to intravenous and intra-arterial intervention.

Identifiants

pubmed: 31030187
pii: neurintsurg-2019-014890
doi: 10.1136/neurintsurg-2019-014890
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1080-1084

Informations de copyright

© Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

Auteurs

Jody Manners (J)

Neurology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

Namir Khandker (N)

Critical Care Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

Adam Barron (A)

Neurology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

Yasmin Aziz (Y)

Neurology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

Shashvat M Desai (SM)

Neurology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

Benjamin Morrow (B)

Stroke Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

William T Delfyett (WT)

Radiology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.

Christian Martin-Gill (C)

Emergency Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.

Lori Shutter (L)

Critical Care Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

Tudor G Jovin (TG)

Neurology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

Ashutosh P Jadhav (AP)

Neurology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

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