Expanding Research Capacity in Sub-Saharan Africa Through Informatics, Bioinformatics, and Data Science Training Programs in Mali.

Human Heredity and Health in Africa (H3Africa) bioinformatics data capture and management systems data science genetics genomics malaria training

Journal

Frontiers in genetics
ISSN: 1664-8021
Titre abrégé: Front Genet
Pays: Switzerland
ID NLM: 101560621

Informations de publication

Date de publication:
2019
Historique:
received: 16 11 2018
accepted: 28 03 2019
entrez: 30 4 2019
pubmed: 30 4 2019
medline: 30 4 2019
Statut: epublish

Résumé

Bioinformatics and data science research have boundless potential across Africa due to its high levels of genetic diversity and disproportionate burden of infectious diseases, including malaria, tuberculosis, HIV and AIDS, Ebola virus disease, and Lassa fever. This work lays out an incremental approach for reaching underserved countries in bioinformatics and data science research through a progression of capacity building, training, and research efforts. Two global health informatics training programs sponsored by the Fogarty International Center (FIC) were carried out at the University of Sciences, Techniques and Technologies of Bamako, Mali (USTTB) between 1999 and 2011. Together with capacity building efforts through the West Africa International Centers of Excellence in Malaria Research (ICEMR), this progress laid the groundwork for a bioinformatics and data science training program launched at USTTB as part of the Human Heredity and Health in Africa (H3Africa) initiative. Prior to the global health informatics training, its trainees published first or second authorship and third or higher authorship manuscripts at rates of 0.40 and 0.10 per year, respectively. Following the training, these rates increased to 0.70 and 1.23 per year, respectively, which was a statistically significant increase (

Identifiants

pubmed: 31031807
doi: 10.3389/fgene.2019.00331
pmc: PMC6473184
doi:

Types de publication

Journal Article

Langues

eng

Pagination

331

Subventions

Organisme : FIC NIH HHS
ID : D43 TW008652
Pays : United States
Organisme : NIAID NIH HHS
ID : U19 AI089696
Pays : United States
Organisme : NIAID NIH HHS
ID : U19 AI129387
Pays : United States
Organisme : FIC NIH HHS
ID : U2R TW010673
Pays : United States

Références

PLoS Biol. 2004 Dec;2(12):e372
pubmed: 15597114
Bull World Health Organ. 2004 Oct;82(10):764-70
pubmed: 15643798
Bull World Health Organ. 2005 Aug;83(8):578-83
pubmed: 16184276
BMC Health Serv Res. 2006 Oct 19;6:135
pubmed: 17052326
Afr J Med Med Sci. 2007;36 Suppl:31-3
pubmed: 17703561
Annu Rev Genomics Hum Genet. 2008;9:403-33
pubmed: 18593304
Science. 2009 May 22;324(5930):1035-44
pubmed: 19407144
J Med Libr Assoc. 2009 Oct;97(4):241-3; author reply 243
pubmed: 19851485
PLoS Med. 2010 Jul 06;7(7):e1000299
pubmed: 20625547
Science. 2010 Oct 29;330(6004):686-8
pubmed: 20929725
Stat Med. 2011 Mar 30;30(7):695-708
pubmed: 21394746
Malar J. 2011 Nov 10;10:339
pubmed: 22074219
Acta Trop. 2012 Mar;121(3):175-83
pubmed: 22142790
Am J Trop Med Hyg. 2012 Jul;87(1):23-8
pubmed: 22764287
Am J Trop Med Hyg. 2012 Aug;87(2):231-241
pubmed: 22855752
Malar J. 2013 Mar 04;12:86
pubmed: 23496910
BMC Public Health. 2013 Mar 22;13:258
pubmed: 23517572
Online J Public Health Inform. 2012;4(3):null
pubmed: 23569646
PLoS Negl Trop Dis. 2014 Mar 20;8(3):e2748
pubmed: 24651047
Source Code Biol Med. 2014 May 08;9:10
pubmed: 24829612
Science. 2014 Jun 20;344(6190):1346-8
pubmed: 24948725
Brief Bioinform. 2015 Mar;16(2):355-64
pubmed: 24990350
Malar J. 2014 Sep 12;13:358
pubmed: 25217396
N Engl J Med. 2014 Nov 27;371(22):2092-100
pubmed: 25353969
Ann N Y Acad Sci. 2015 Apr;1342:62-7
pubmed: 25891142
Am J Trop Med Hyg. 2015 Sep;93(3 Suppl):124-132
pubmed: 26259944
PLoS Comput Biol. 2015 Sep 17;11(9):e1004308
pubmed: 26378921
Vaccine. 2015 Dec 22;33(52):7452-61
pubmed: 26469720
Am J Trop Med Hyg. 2016 Feb;94(2):253-257
pubmed: 26598570
Genome Res. 2016 Feb;26(2):271-7
pubmed: 26627985
Appl Transl Genom. 2015 Sep;6:31-34
pubmed: 26767162
Appl Transl Genom. 2015 Sep;6:35-41
pubmed: 26767163
Am J Trop Med Hyg. 2016 Mar;94(3):634-9
pubmed: 26811430
Lancet Infect Dis. 2016 Jun;16(6):674-684
pubmed: 26906747
Mol Genet Genomic Med. 2016 Mar 17;4(2):126-34
pubmed: 27066513
PLoS Negl Trop Dis. 2016 Nov 29;10(11):e0005141
pubmed: 27898671
Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):1740-1742
pubmed: 28228604
Glob Heart. 2017 Jun;12(2):91-98
pubmed: 28302555
Clin Infect Dis. 2017 Mar 1;64(5):645-653
pubmed: 28362910
Genet Med. 2017 Jul;19(7):826-833
pubmed: 28383545
Lancet Glob Health. 2017 Aug;5(8):e772-e781
pubmed: 28668230
Genomics. 2018 Jan;110(1):1-9
pubmed: 28774809
Lancet Infect Dis. 2017 Dec;17(12):1266-1275
pubmed: 28916443
Brief Bioinform. 2019 Mar 22;20(2):398-404
pubmed: 28968751
PLoS Comput Biol. 2017 Oct 5;13(10):e1005715
pubmed: 28981516
Malar J. 2017 Oct 23;16(1):420
pubmed: 29058578
PLoS Comput Biol. 2018 Feb 1;14(2):e1005772
pubmed: 29390004
Pharmgenomics Pers Med. 2018 Apr 10;11:59-66
pubmed: 29692621
Infect Genet Evol. 2018 Dec;66:222-228
pubmed: 30316883
Infect Dis Poverty. 2018 Nov 16;7(1):125
pubmed: 30541626
Am J Trop Med Hyg. 1998 Feb;58(2):127-32
pubmed: 9502592

Auteurs

Jeffrey G Shaffer (JG)

Department of Global Biostatistics and Data Science, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, United States.

Frances J Mather (FJ)

Department of Global Biostatistics and Data Science, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, United States.

Mamadou Wele (M)

Faculty of Medicine and Odontostomatology, University of Sciences, Techniques and Technologies of Bamako, Bamako, Mali.

Jian Li (J)

Department of Global Biostatistics and Data Science, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, United States.

Cheick Oumar Tangara (CO)

Faculty of Medicine and Odontostomatology, University of Sciences, Techniques and Technologies of Bamako, Bamako, Mali.

Yaya Kassogue (Y)

Faculty of Medicine and Odontostomatology, University of Sciences, Techniques and Technologies of Bamako, Bamako, Mali.

Sudesh K Srivastav (SK)

Department of Global Biostatistics and Data Science, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, United States.

Oumar Thiero (O)

Faculty of Medicine and Odontostomatology, University of Sciences, Techniques and Technologies of Bamako, Bamako, Mali.

Mahamadou Diakite (M)

Faculty of Medicine and Odontostomatology, University of Sciences, Techniques and Technologies of Bamako, Bamako, Mali.

Modibo Sangare (M)

Faculty of Medicine and Odontostomatology, University of Sciences, Techniques and Technologies of Bamako, Bamako, Mali.

Djeneba Dabitao (D)

Faculty of Medicine and Odontostomatology, University of Sciences, Techniques and Technologies of Bamako, Bamako, Mali.

Mahamoudou Toure (M)

Faculty of Medicine and Odontostomatology, University of Sciences, Techniques and Technologies of Bamako, Bamako, Mali.

Abdoulaye A Djimde (AA)

Faculty of Medicine and Odontostomatology, University of Sciences, Techniques and Technologies of Bamako, Bamako, Mali.

Sekou Traore (S)

Faculty of Medicine and Odontostomatology, University of Sciences, Techniques and Technologies of Bamako, Bamako, Mali.

Brehima Diakite (B)

Faculty of Medicine and Odontostomatology, University of Sciences, Techniques and Technologies of Bamako, Bamako, Mali.

Mamadou B Coulibaly (MB)

Faculty of Medicine and Odontostomatology, University of Sciences, Techniques and Technologies of Bamako, Bamako, Mali.

Yaozhong Liu (Y)

Department of Global Biostatistics and Data Science, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, United States.

Michelle Lacey (M)

Department of Mathematics, Tulane University, New Orleans, LA, United States.

John J Lefante (JJ)

Department of Global Biostatistics and Data Science, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, United States.

Ousmane Koita (O)

Faculty of Medicine and Odontostomatology, University of Sciences, Techniques and Technologies of Bamako, Bamako, Mali.

John S Schieffelin (JS)

Sections of Pediatric & Adult Infectious Diseases, School of Medicine, Tulane University, New Orleans, LA, United States.

Donald J Krogstad (DJ)

Department of Global Biostatistics and Data Science, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, United States.

Seydou O Doumbia (SO)

Faculty of Medicine and Odontostomatology, University of Sciences, Techniques and Technologies of Bamako, Bamako, Mali.

Classifications MeSH