Drug-Induced Sleep Endoscopy Upper Airway Collapse Patterns and Maxillomandibular Advancement.


Journal

The Laryngoscope
ISSN: 1531-4995
Titre abrégé: Laryngoscope
Pays: United States
ID NLM: 8607378

Informations de publication

Date de publication:
04 2020
Historique:
received: 30 10 2018
revised: 28 03 2019
accepted: 03 04 2019
pubmed: 30 4 2019
medline: 25 8 2020
entrez: 30 4 2019
Statut: ppublish

Résumé

To evaluate upper airway (UA) collapse patterns during drug-induced sleep endoscopy (DISE) and maxillomandibular advancement (MMA) surgery outcome, paying particular attention to the DISE phenotype complete concentric collapse at the level of the palate (CCCp). Prospective case series. Nineteen patients diagnosed with obstructive sleep apnea (OSA) prospectively underwent mandibular advancement device (MAD) treatment followed by MMA surgery. UA collapse patterns were evaluated before and after MMA surgery. Baseline apnea-hypopnea index (AHI) was compared with AHI during MAD treatment and after MMA surgery. UA collapse patterns and the presence of baseline CCCp were assessed. AHI differences between patients with and without CCCp after MMA surgery were compared. In 14 patients, a full dataset was obtained: 8/6 (male/female), mean age = 51 ± 7 years, body mass index (BMI) = 25.6 ± 3.7 kg/m CCCp seems not to be a negative predictor for MMA surgery outcome measured by AHI reduction. Furthermore, MMA is likely to eliminate CCCp. Therefore, MMA might be a solution for OSA patients showing CCCp and broadens the perspective for personalized medicine and combination therapy. However, a large sample is required for definitive results. 4 Laryngoscope, 130:E268-E274, 2020.

Identifiants

pubmed: 31034634
doi: 10.1002/lary.28022
doi:

Substances chimiques

Hypnotics and Sedatives 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

E268-E274

Informations de copyright

© 2019 The American Laryngological, Rhinological and Otological Society, Inc.

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Auteurs

Chloé Kastoer (C)

Department of Otorhinolaryngology-Head and Neck Surgery, Antwerp University Hospital, Edegem, Antwerp, Belgium.
Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Antwerp, Belgium.

Sara Op de Beeck (S)

Department of Otorhinolaryngology-Head and Neck Surgery, Antwerp University Hospital, Edegem, Antwerp, Belgium.
Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Antwerp, Belgium.

Marc Dom (M)

Department of Special Care Dentistry, Antwerp University Hospital, Edegem, Antwerp, Belgium.

Thérèse Neirinckx (T)

Department of Special Care Dentistry, Antwerp University Hospital, Edegem, Antwerp, Belgium.

Johan Verbraecken (J)

Multidisciplinary Sleep Disorders Centre, Antwerp University Hospital, Edegem, Antwerp, Belgium.
Department of Pulmonology, Antwerp University Hospital, Edegem, Antwerp, Belgium.

Marc J Braem (MJ)

Department of Special Care Dentistry, Antwerp University Hospital, Edegem, Antwerp, Belgium.
Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Antwerp, Belgium.

Paul H Van de Heyning (PH)

Department of Otorhinolaryngology-Head and Neck Surgery, Antwerp University Hospital, Edegem, Antwerp, Belgium.
Multidisciplinary Sleep Disorders Centre, Antwerp University Hospital, Edegem, Antwerp, Belgium.
Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Antwerp, Belgium.

Nasser Nadjmi (N)

Department of Oral and Cranio-Maxillofacial Surgery, Antwerp University Hospital, Edegem, Antwerp, Belgium.
Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Antwerp, Belgium.

Olivier M Vanderveken (OM)

Department of Otorhinolaryngology-Head and Neck Surgery, Antwerp University Hospital, Edegem, Antwerp, Belgium.
Multidisciplinary Sleep Disorders Centre, Antwerp University Hospital, Edegem, Antwerp, Belgium.
Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Antwerp, Belgium.

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