Water-Mediated Nanostructures for Enhanced MRI: Impact of Water Dynamics on Relaxometric Properties of Gd-DTPA.

Biopolymers / chemistry Calorimetry, Differential Scanning Contrast Media / chemistry Gadolinium DTPA / chemistry Hydrogels / chemistry Magnetic Resonance Imaging / methods Magnetic Resonance Spectroscopy Nanostructures / chemistry
MRI contrast agents hydrodenticity hydrogels nanoparticles

Journal

Theranostics
ISSN: 1838-7640
Titre abrégé: Theranostics
Pays: Australia
ID NLM: 101552395

Informations de publication

Date de publication:
2019
Historique:
received: 17 05 2018
accepted: 19 01 2019
entrez: 1 5 2019
pubmed: 1 5 2019
medline: 17 3 2020
Statut: epublish

Résumé

Recently, rational design of a new class of contrast agents (CAs), based on biopolymers (hydrogels), have received considerable attention in Magnetic Resonance Imaging (MRI) diagnostic field. Several strategies have been adopted to improve relaxivity without chemical modification of the commercial CAs, however, understanding the MRI enhancement mechanism remains a challenge.

Identifiants

DOI: 10.7150/thno.27313 PMID: 31037140 PMC: PMC6485182
pubmed: 31037140
doi: 10.7150/thno.27313
pii: thnov09p1809
pmc: PMC6485182
doi:

Substances chimiques

Biopolymers 0
Contrast Media 0
Hydrogels 0
Gadolinium DTPA K2I13DR72L

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1809-1824

Déclaration de conflit d'intérêts

Competing Interests: The authors have declared that no competing interest exists.

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Auteurs

Franca De Sarno (F)

Department of Chemical, Materials Engineering & Industrial Production, University of Naples Federico II, Piazzale Tecchio 80, 80125 Naples, Italy.
Center for Advanced Biomaterials for Health Care, CABHC, Istituto Italiano di Tecnologia, IIT@CRIB, Largo Barsanti e Matteucci 53, 80125 Naples, Italy.

Alfonso Maria Ponsiglione (AM)

Department of Chemical, Materials Engineering & Industrial Production, University of Naples Federico II, Piazzale Tecchio 80, 80125 Naples, Italy.
Center for Advanced Biomaterials for Health Care, CABHC, Istituto Italiano di Tecnologia, IIT@CRIB, Largo Barsanti e Matteucci 53, 80125 Naples, Italy.

Maria Russo (M)

Department of Chemical, Materials Engineering & Industrial Production, University of Naples Federico II, Piazzale Tecchio 80, 80125 Naples, Italy.
Center for Advanced Biomaterials for Health Care, CABHC, Istituto Italiano di Tecnologia, IIT@CRIB, Largo Barsanti e Matteucci 53, 80125 Naples, Italy.

Anna Maria Grimaldi (AM)

IRCCS SDN, Via E. Gianturco 113, 80143 Naples, Italy.

Ernesto Forte (E)

IRCCS SDN, Via E. Gianturco 113, 80143 Naples, Italy.

Paolo Antonio Netti (PA)

Department of Chemical, Materials Engineering & Industrial Production, University of Naples Federico II, Piazzale Tecchio 80, 80125 Naples, Italy.
Center for Advanced Biomaterials for Health Care, CABHC, Istituto Italiano di Tecnologia, IIT@CRIB, Largo Barsanti e Matteucci 53, 80125 Naples, Italy.
Interdisciplinary Research Center on Biomaterials, CRIB, Piazzale Tecchio 80, 80125 Naples, Italy.

Enza Torino (E)

Department of Chemical, Materials Engineering & Industrial Production, University of Naples Federico II, Piazzale Tecchio 80, 80125 Naples, Italy.
Center for Advanced Biomaterials for Health Care, CABHC, Istituto Italiano di Tecnologia, IIT@CRIB, Largo Barsanti e Matteucci 53, 80125 Naples, Italy.
Interdisciplinary Research Center on Biomaterials, CRIB, Piazzale Tecchio 80, 80125 Naples, Italy.

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Classifications MeSH

questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Matériaux biomédicaux et dentaires › Polymères › Biopolymères › Water-Mediated Nanostructures for Enhanced...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Analyse thermique différentielle › Calorimétrie différentielle à balayage › Water-Mediated Nanostructures for Enhanced...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Produits de contraste › Water-Mediated Nanostructures for Enhanced...
questionsmedicales.fr › Composés chimiques organiques › Complexes de coordination › Acide gadopentétique › Water-Mediated Nanostructures for Enhanced...
questionsmedicales.fr › Préparations pharmaceutiques › Colloïdes › Gels › Hydrogels › Water-Mediated Nanostructures for Enhanced...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Imagerie diagnostique › Tomographie › Imagerie par résonance magnétique › Water-Mediated Nanostructures for Enhanced...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Analyse spectrale › Spectroscopie par résonance magnétique › Water-Mediated Nanostructures for Enhanced...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Nanostructures › Water-Mediated Nanostructures for Enhanced...