[The greater wax moth, Galleria mellonella to study host-pathogen interactions].
La teigne Galleria mellonella pour les études hôte-pathogène.
Journal
Medecine sciences : M/S
ISSN: 1958-5381
Titre abrégé: Med Sci (Paris)
Pays: France
ID NLM: 8710980
Informations de publication
Date de publication:
Apr 2019
Apr 2019
Historique:
entrez:
1
5
2019
pubmed:
1
5
2019
medline:
19
12
2019
Statut:
ppublish
Résumé
The massive use of antibiotics in health and agriculture has led to the emergence of pathogenic microorganisms resistant to frequently used treatments. In 2017, the World Health Organization (WHO) published its first ever list of antibiotic-resistant "priority pathogens", a catalogue of twelve families of bacteria that pose the greatest threat to human health. In this context, a new model for the study of host-pathogen interactions is becoming increasingly popular : the greater wax moth, Galleria mellonella. This butterfly larvae, sometimes considered as a new "laboratory rat", has many practical advantages and is an important host in the study of some steps in the pathogenicity of infectious agents and the identification of new treatments. This review presents this alternative model and describes its possible applications.
Identifiants
pubmed: 31038112
doi: 10.1051/medsci/2019071
pii: msc190043
doi:
Substances chimiques
Anti-Bacterial Agents
0
Types de publication
Journal Article
Review
Langues
fre
Sous-ensembles de citation
IM
Pagination
346-351Informations de copyright
© 2019 médecine/sciences – Inserm.