The incidence of idiopathic intracranial hypertension in Scotland: a SOSU study.
Journal
Eye (London, England)
ISSN: 1476-5454
Titre abrégé: Eye (Lond)
Pays: England
ID NLM: 8703986
Informations de publication
Date de publication:
10 2019
10 2019
Historique:
received:
04
10
2018
accepted:
06
03
2019
revised:
26
02
2019
pubmed:
2
5
2019
medline:
27
11
2020
entrez:
2
5
2019
Statut:
ppublish
Résumé
Idiopathic intracranial hypertension most commonly affects women of childbearing age and usually causes headache and intermittent visual obscurations. Some patients suffer permanent visual loss. The major modifiable risk factor associated with IIH is obesity. Scotland has one of the poorest records for obesity in the western world, with a prevalence in 2016 of 29% in the adult population. We aimed to establish the incidence of idiopathic intracranial hypertension (IIH) in Scotland. All new cases of IIH seen in Scotland were collected over a 1-year period. Cases were reported by ophthalmologists through the Scottish Ophthalmic Surveillance Unit (SOSU) and by neurologists directly to the investigators using encrypted NHS emails. An open dialogue was maintained between the investigators and specialist neuro-ophthalmology clinics throughout the year to minimise the risk of under-reporting. Cases were defined using the Modified Dandy Diagnostic Criteria. One hundred and forty-four confirmed cases of IIH were reported. One hundred and ten out of 144 patients were female and aged 15-44. The mean BMI in this group was 38.9. The incidence of IIH in Scotland is at least 2.65/100,000. This figure rises to 37.9/100,000 in obese females aged 15-44. This figure is higher than previously published and is probably a result of increasing levels of obesity across the nation. The significant morbidity caused by IIH, in this young population raises the question of whether enough is being done to prevent and treat Scotland's obesity crisis.
Sections du résumé
BACKGROUND
Idiopathic intracranial hypertension most commonly affects women of childbearing age and usually causes headache and intermittent visual obscurations. Some patients suffer permanent visual loss. The major modifiable risk factor associated with IIH is obesity. Scotland has one of the poorest records for obesity in the western world, with a prevalence in 2016 of 29% in the adult population. We aimed to establish the incidence of idiopathic intracranial hypertension (IIH) in Scotland.
METHODS
All new cases of IIH seen in Scotland were collected over a 1-year period. Cases were reported by ophthalmologists through the Scottish Ophthalmic Surveillance Unit (SOSU) and by neurologists directly to the investigators using encrypted NHS emails. An open dialogue was maintained between the investigators and specialist neuro-ophthalmology clinics throughout the year to minimise the risk of under-reporting. Cases were defined using the Modified Dandy Diagnostic Criteria.
RESULTS
One hundred and forty-four confirmed cases of IIH were reported. One hundred and ten out of 144 patients were female and aged 15-44. The mean BMI in this group was 38.9.
CONCLUSIONS
The incidence of IIH in Scotland is at least 2.65/100,000. This figure rises to 37.9/100,000 in obese females aged 15-44. This figure is higher than previously published and is probably a result of increasing levels of obesity across the nation. The significant morbidity caused by IIH, in this young population raises the question of whether enough is being done to prevent and treat Scotland's obesity crisis.
Identifiants
pubmed: 31040381
doi: 10.1038/s41433-019-0450-y
pii: 10.1038/s41433-019-0450-y
pmc: PMC7002681
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1570-1576Références
Neurology. 1991 Feb;41(2 ( Pt 1)):239-44
pubmed: 1992368
Eur J Ophthalmol. 2004 Jan-Feb;14(1):48-54
pubmed: 15005585
Ulster Med J. 2001 May;70(1):31-5
pubmed: 11428322
Acta Neurol Scand. 2017 Nov;136(5):427-433
pubmed: 28244170
Acta Neurol Scand. 2010 Feb;121(2):71-82
pubmed: 19930211
Open Ophthalmol J. 2013 Jun 28;7:26-9
pubmed: 23898356
Arch Neurol. 1993 Jan;50(1):78-80
pubmed: 8418804
J Neuroophthalmol. 2001 Mar;21(1):12-4
pubmed: 11315973
Ophthalmology. 2017 May;124(5):697-700
pubmed: 28187976
J Neurol. 2000 Jun;247(6):474-5
pubmed: 10929282
J Neurol Sci. 2004 Aug 30;223(2):157-60
pubmed: 15337617
Neurology. 2016 Jan 26;86(4):341-50
pubmed: 26718577
Eur J Neurol. 2018 Oct;25(10):1218-1227
pubmed: 29953685
Arch Neurol. 1990 Mar;47(3):315-20
pubmed: 2310315
Int J Obes Relat Metab Disord. 1999 Jan;23(1):54-9
pubmed: 10094577
J Neurol Neurosurg Psychiatry. 2018 Oct;89(10):1088-1100
pubmed: 29903905
Neurology. 2002 Nov 26;59(10):1492-5
pubmed: 12455560
Scott Med J. 2019 May;64(2):62-66
pubmed: 30396313
Am J Ophthalmol. 2007 Apr;143(4):635-41
pubmed: 17386271
Neuroepidemiology. 2015;45(1):34-9
pubmed: 26201454
Arch Neurol. 1988 Aug;45(8):875-7
pubmed: 3395261
Eur J Neurol. 2011 Oct;18(10):1266-8
pubmed: 21426442