Co-localization of autophagy-related protein p62 with cancer stem cell marker dclk1 may hamper dclk1's elimination during colon cancer development and progression.
autophagy
colon cancer
dclk1
metastasis
stem cells
Journal
Oncotarget
ISSN: 1949-2553
Titre abrégé: Oncotarget
Pays: United States
ID NLM: 101532965
Informations de publication
Date de publication:
22 Mar 2019
22 Mar 2019
Historique:
received:
10
01
2019
accepted:
01
02
2019
entrez:
2
5
2019
pubmed:
2
5
2019
medline:
2
5
2019
Statut:
epublish
Résumé
Autophagy may play a critical role in colon cancer stem cells (CCSCs)-related cancer development. Here, we investigate whether accumulation of infection/injury-induced CCSCs due to impaired autophagy influences colon cancer development and progression. When
Identifiants
pubmed: 31040926
doi: 10.18632/oncotarget.26684
pii: 26684
pmc: PMC6481322
doi:
Types de publication
Journal Article
Langues
eng
Pagination
2340-2354Subventions
Organisme : NCI NIH HHS
ID : R01 CA185322
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA190291
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK117296
Pays : United States
Déclaration de conflit d'intérêts
CONFLICTS OF INTEREST The authors declare no conflict of interest.
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