Safety of bivalirudin versus unfractionated heparin in endovascular revascularization of peripheral arteries in short- and long-term follow-up.
bivalirudin
heparin
long-term mortality
peripheral artery disease
Journal
Postepy w kardiologii interwencyjnej = Advances in interventional cardiology
ISSN: 1734-9338
Titre abrégé: Postepy Kardiol Interwencyjnej
Pays: Poland
ID NLM: 101272671
Informations de publication
Date de publication:
2019
2019
Historique:
received:
27
05
2018
accepted:
04
11
2018
entrez:
3
5
2019
pubmed:
3
5
2019
medline:
3
5
2019
Statut:
ppublish
Résumé
Patients with peripheral artery disease (PAD) are considered as a high-risk group for hemorrhagic events. To assess the safety of bivalirudin vs. unfractionated heparin (UFH) in percutaneous peripheral interventions (PPI) in short- and long-term follow-up. The retrospective single-center, observational study included 160 patients, undergoing PPI. Patients were divided into 2 groups based on the use of anticoagulation - unfractionated heparin (UFH group) or bivalirudin (Biv. group) - and observed up to 5 years. The UFH group consisted of 101 patients and the Biv. group consisted of 59. We registered the following end points during in-hospital observation: 1 death (0.63% Biv, Usage of UFH was associated with a higher number of hemorrhagic complications, especially hematomas at the puncture site in comparison to patients receiving bivalirudin.
Identifiants
pubmed: 31043990
doi: 10.5114/aic.2019.81757
pii: 34960
pmc: PMC6488834
doi:
Types de publication
Journal Article
Langues
eng
Pagination
91-97Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
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