Chinese Women in Both the United States and Hong Kong Have Cortical Microstructural Advantages and More Trabecular Plates Compared With White Women.

CHINESE HONG KONG HR‐pQCT ITS MICROARCHITECTURE RACE WHITE WOMEN

Journal

JBMR plus
ISSN: 2473-4039
Titre abrégé: JBMR Plus
Pays: England
ID NLM: 101707013

Informations de publication

Date de publication:
Apr 2019
Historique:
received: 29 05 2018
revised: 07 08 2018
accepted: 12 08 2018
entrez: 3 5 2019
pubmed: 3 5 2019
medline: 3 5 2019
Statut: epublish

Résumé

We cross-sectionally compared racial differences in bone quality between Chinese women in the United States (US) and Hong Kong (HK) with white women. A total of 514 women were included. We measured bone geometry, mass, microstructure, and stiffness by high-resolution peripheral quantitative computed tomography (HR-pQCT), individual trabecula segmentation (ITS), and microfinite element analysis (μFEA). After adjustment for age and body mass index (BMI), premenopausal Chinese women in the US and HK had smaller bone area but greater radial cortical (Ct.) thickness and Ct. and trabecular (Tb.) volumetric bone mineral density (vBMD) versus white women but did not differ from each other. At the radius, Tb. number was lower and spacing greater in Chinese women from HK and the US versus white women, whereas Chinese women did not differ from each other. Tb. thickness was highest in Chinese women from HK, intermediate in Chinese-Americans, and lowest in white women. Chinese women had more trabecular plates versus white women, leading to greater age- and BMI-adjusted stiffness for premenopausal Chinese women in HK and the US (both

Identifiants

pubmed: 31044182
doi: 10.1002/jbm4.10083
pii: JBM410083
pmc: PMC6478582
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e10083

Informations de copyright

© 2018 American Society for Bone and Mineral Research.

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Auteurs

Melissa Sum (M)

Division of Endocrinology Department of Medicine New York University Langone Health Medical Center New York NY USA.

Tracy Y Zhu (TY)

Bone Quality and Health Assessment Center of the Department of Orthopaedics and Traumatology the Chinese University of Hong Kong Hong Kong SAR PR China.

Bin Zhou (B)

Bone Bioengineering Laboratory Department of Biomedical Engineering Fu Foundation School of Engineering and Applied Science Columbia University New York NY USA.

Zhendong Zhang (Z)

Department of Orthopedic Surgery First Affiliated Hospital School of Medicine Shihezi University Shihezi China.

John P Bilezikian (JP)

Division of Endocrinology Department of Medicine Columbia University College of Physicians and Surgeons New York NY USA.

X Edward Guo (XE)

Bone Bioengineering Laboratory Department of Biomedical Engineering Fu Foundation School of Engineering and Applied Science Columbia University New York NY USA.

Ling Qin (L)

Bone Quality and Health Assessment Center of the Department of Orthopaedics and Traumatology the Chinese University of Hong Kong Hong Kong SAR PR China.

Marcella Walker (M)

Division of Endocrinology Department of Medicine Columbia University College of Physicians and Surgeons New York NY USA.

Classifications MeSH