Regional anticoagulation with heparin of an extracorporeal CO
Anticoagulants
/ administration & dosage
Carbon Dioxide
/ blood
Disease Progression
Extracorporeal Circulation
Extracorporeal Membrane Oxygenation
Heparin
/ administration & dosage
Humans
Male
Middle Aged
Pulmonary Disease, Chronic Obstructive
/ complications
Respiration, Artificial
Treatment Outcome
Continuous venovenous filtration
Extracorporeal CO2 removal
Heparin regional anticoagulation
Journal
Journal of medical case reports
ISSN: 1752-1947
Titre abrégé: J Med Case Rep
Pays: England
ID NLM: 101293382
Informations de publication
Date de publication:
03 May 2019
03 May 2019
Historique:
received:
03
12
2018
accepted:
13
03
2019
entrez:
4
5
2019
pubmed:
3
5
2019
medline:
4
12
2019
Statut:
epublish
Résumé
Extracorporeal carbon dioxide removal is an increasingly used respiratory support technique. As is true of all extracorporeal techniques, extracorporeal carbon dioxide removal needs proper anticoagulation. We report a case of a patient at risk of bleeding complications who was treated with extracorporeal carbon dioxide removal and anticoagulated with a regional technique. A 56-year-old Caucasian man with a history of chronic obstructive pulmonary disease exacerbation required extracorporeal carbon dioxide removal for severe hypercapnia and acidosis despite mechanical ventilation. The extracorporeal circuit was anticoagulated using a regional heparin technique to limit the patient's risk of bleeding due to a low platelet count. The patient underwent 96 h of effective extracorporeal carbon dioxide removal without any adverse events. He was successfully weaned from extracorporeal carbon dioxide removal. During the treatment, no bleeding complications or unexpected circuit clotting was observed. The use of regional heparin anticoagulation technique seems to be feasible and safe during extracorporeal carbon dioxide removal.
Sections du résumé
BACKGROUND
BACKGROUND
Extracorporeal carbon dioxide removal is an increasingly used respiratory support technique. As is true of all extracorporeal techniques, extracorporeal carbon dioxide removal needs proper anticoagulation. We report a case of a patient at risk of bleeding complications who was treated with extracorporeal carbon dioxide removal and anticoagulated with a regional technique.
CASE PRESENTATION
METHODS
A 56-year-old Caucasian man with a history of chronic obstructive pulmonary disease exacerbation required extracorporeal carbon dioxide removal for severe hypercapnia and acidosis despite mechanical ventilation. The extracorporeal circuit was anticoagulated using a regional heparin technique to limit the patient's risk of bleeding due to a low platelet count. The patient underwent 96 h of effective extracorporeal carbon dioxide removal without any adverse events. He was successfully weaned from extracorporeal carbon dioxide removal. During the treatment, no bleeding complications or unexpected circuit clotting was observed.
CONCLUSIONS
CONCLUSIONS
The use of regional heparin anticoagulation technique seems to be feasible and safe during extracorporeal carbon dioxide removal.
Identifiants
pubmed: 31046832
doi: 10.1186/s13256-019-2051-6
pii: 10.1186/s13256-019-2051-6
pmc: PMC6498662
doi:
Substances chimiques
Anticoagulants
0
Carbon Dioxide
142M471B3J
Heparin
9005-49-6
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
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