Incidence of myopotential induction in subcutaneous implantable cardioverter-defibrillator patients: Is the oversensing issue really solved?


Journal

Heart rhythm
ISSN: 1556-3871
Titre abrégé: Heart Rhythm
Pays: United States
ID NLM: 101200317

Informations de publication

Date de publication:
10 2019
Historique:
received: 07 12 2018
pubmed: 3 5 2019
medline: 2 12 2020
entrez: 4 5 2019
Statut: ppublish

Résumé

The subcutaneous implantable cardioverter-defibrillator (S-ICD) has established its role in the prevention of sudden cardiac death in a defined population. Inappropriate shocks and device malfunction in S-ICD therapy may be caused by myopotential (MP) oversensing. The purpose of this study was to systematically evaluate a cohort of consecutive S-ICD patients for MP inducibility. After S-ICD implantation, all vectors (primary [PrimV], secondary [SecV], alternative [AltV]) were analyzed during isometric chest press (ICP), lifting and holding a 20-kg weight, and side plank exercise (SPE), supporting the body weight on the left arm. When MPs were induced, signal classification was assessed: adequate noise detection, induced undersensing (R waves classified as noise), and oversensing (noise annotated as R waves). In case of noise induction in the current vector, device reprogramming to a noise-free vector was done. We systematically assessed 41 patients. In nearly all patients (90.2%), MPs were inducible. ICP was the most potent inductor of MPs. Whereas SecV (70.7%) and AltV (75.6%) were most vulnerable during ICP, PrimV was most affected during SPE (51.2%). In only a few cases did the S-ICD software distinguish correctly between MPs and QRS. MPs predominantly led to undersensing (up to 65.9%), but in up to 22% of patients MP-induced oversensing occurred but did not lead to tachycardia detection. No relation was seen between S-ICD lead and generator position and MP inducibility. Induction of MPs during physical exercise was observed frequently. Although in most cases MP noise led to undersensing, oversensing events were commonly observed.

Sections du résumé

BACKGROUND
The subcutaneous implantable cardioverter-defibrillator (S-ICD) has established its role in the prevention of sudden cardiac death in a defined population. Inappropriate shocks and device malfunction in S-ICD therapy may be caused by myopotential (MP) oversensing.
OBJECTIVE
The purpose of this study was to systematically evaluate a cohort of consecutive S-ICD patients for MP inducibility.
METHODS
After S-ICD implantation, all vectors (primary [PrimV], secondary [SecV], alternative [AltV]) were analyzed during isometric chest press (ICP), lifting and holding a 20-kg weight, and side plank exercise (SPE), supporting the body weight on the left arm. When MPs were induced, signal classification was assessed: adequate noise detection, induced undersensing (R waves classified as noise), and oversensing (noise annotated as R waves). In case of noise induction in the current vector, device reprogramming to a noise-free vector was done.
RESULTS
We systematically assessed 41 patients. In nearly all patients (90.2%), MPs were inducible. ICP was the most potent inductor of MPs. Whereas SecV (70.7%) and AltV (75.6%) were most vulnerable during ICP, PrimV was most affected during SPE (51.2%). In only a few cases did the S-ICD software distinguish correctly between MPs and QRS. MPs predominantly led to undersensing (up to 65.9%), but in up to 22% of patients MP-induced oversensing occurred but did not lead to tachycardia detection. No relation was seen between S-ICD lead and generator position and MP inducibility.
CONCLUSION
Induction of MPs during physical exercise was observed frequently. Although in most cases MP noise led to undersensing, oversensing events were commonly observed.

Identifiants

pubmed: 31048064
pii: S1547-5271(19)30427-8
doi: 10.1016/j.hrthm.2019.04.044
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1523-1530

Informations de copyright

Copyright © 2019 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved.

Auteurs

Jan-Hendrik van den Bruck (JH)

University of Cologne, Department of Electrophysiology, University Hospital Cologne, Cologne, Germany. Electronic address: Jan-Hendrik.van-den-bruck@uk-koeln.de.

Arian Sultan (A)

University of Cologne, Department of Electrophysiology, University Hospital Cologne, Cologne, Germany.

Tobias Plenge (T)

University of Cologne, Department of Electrophysiology, University Hospital Cologne, Cologne, Germany.

Katharina Seuthe (K)

University of Cologne, Department of Electrophysiology, University Hospital Cologne, Cologne, Germany.

Tim Mödder (T)

University of Cologne, Department of Electrophysiology, University Hospital Cologne, Cologne, Germany.

Christos Iliadis (C)

University of Cologne, Department of Electrophysiology, University Hospital Cologne, Cologne, Germany.

Daniel Stern (D)

University of Cologne, Department of Electrophysiology, University Hospital Cologne, Cologne, Germany.

Tatjana Blankenheim (T)

University of Cologne, Department of Electrophysiology, University Hospital Cologne, Cologne, Germany.

Daniel Steven (D)

University of Cologne, Department of Electrophysiology, University Hospital Cologne, Cologne, Germany.

Jakob Lüker (J)

University of Cologne, Department of Electrophysiology, University Hospital Cologne, Cologne, Germany.

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