Rate of Nondiagnostic Computerized Tomography Pulmonary Angiograms (CTPAs) Performed for the Diagnosis of Pulmonary Embolism in Pregnant and Immediately Postpartum Patients.


Journal

Obstetrics and gynecology international
ISSN: 1687-9589
Titre abrégé: Obstet Gynecol Int
Pays: United States
ID NLM: 101517078

Informations de publication

Date de publication:
2019
Historique:
received: 01 08 2018
revised: 11 02 2019
accepted: 12 03 2019
entrez: 4 5 2019
pubmed: 3 5 2019
medline: 3 5 2019
Statut: epublish

Résumé

To evaluate the nondiagnostic rate of computed tomography pulmonary angiography (CTPA) in pregnant and postpartum patients with suspected pulmonary embolism (PE) to determine whether CTPA or ventilation-perfusion (VQ) scan should be considered first line imaging in this patient population considering their equivalent accuracy and the greater radiation exposure to proliferating breast tissue of CTPA. All pregnant/postpartum female patients between 18 and 50 years of age who had CTPA within the Eastern Health Authority between November 2012 and November 2016 were included. Each scan was evaluated for nondiagnosis based on two criteria: contrast density in the main pulmonary artery, and respiratory motion artefact. If either of these criteria were not met, the scan was labelled as nondiagnostic. The nondiagnostic rate overall was 43% ( This is the first study to attempt to identify an objective method of determining nondiagnosis in pregnant and postpartum patients undergoing a CTPA. Our results strengthen the argument that alternative imaging should be considered when investigating for PE in this population in order to protect the proliferating breast tissue, and VQ scan should be considered especially in patients with normal chest X-rays.

Identifiants

pubmed: 31049065
doi: 10.1155/2019/1432759
pmc: PMC6458938
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1432759

Références

Epidemiology. 2001 Jul;12(4):456-60
pubmed: 11416782
Thromb Res. 2001 Sep 15;103(6):V225-38
pubmed: 11567660
Radiology. 2002 Aug;224(2):487-92
pubmed: 12147847
Respir Med. 2006 Oct;100(10):1682-7
pubmed: 16549345
Am J Obstet Gynecol. 2006 May;194(5):1311-5
pubmed: 16647915
BJOG. 2008 Mar;115(4):453-61
pubmed: 18201281
Obstet Gynecol. 2008 Aug;112(2 Pt 1):333-40
pubmed: 18669732
Obstet Gynecol. 2009 Jul;114(1):124-9
pubmed: 19546768
AJR Am J Roentgenol. 2009 Nov;193(5):1223-7
pubmed: 19843734
AJR Am J Roentgenol. 2010 Sep;195(3):W214-20
pubmed: 20729418
Radiology. 2011 Feb;258(2):590-8
pubmed: 21131583
Semin Ultrasound CT MR. 2012 Dec;33(6):500-21
pubmed: 23168061
J Obstet Gynaecol Can. 2014 Jun;36(6):527-53
pubmed: 24927193
Clin Imaging. 2015 Mar-Apr;39(2):251-3
pubmed: 25482354
Breathe (Sheff). 2015 Dec;11(4):282-9
pubmed: 27066121

Auteurs

Sarah Hogan (S)

Memorial University of Newfoundland General Hospital, Health Sciences Centre, 300 Prince Philip Drive, St. John's NL A1B 3V6, Canada.

Jillian Greene (J)

Memorial University of Newfoundland General Hospital, Health Sciences Centre, 300 Prince Philip Drive, St. John's NL A1B 3V6, Canada.

Jeffery Flemming (J)

Memorial University of Newfoundland General Hospital, Health Sciences Centre, 300 Prince Philip Drive, St. John's NL A1B 3V6, Canada.

Classifications MeSH