Primary teeth microhardness and lead (Pb) levels.

Dentistry

Journal

Heliyon
ISSN: 2405-8440
Titre abrégé: Heliyon
Pays: England
ID NLM: 101672560

Informations de publication

Date de publication:
Apr 2019
Historique:
received: 19 09 2018
revised: 10 04 2019
accepted: 17 04 2019
entrez: 4 5 2019
pubmed: 3 5 2019
medline: 3 5 2019
Statut: epublish

Résumé

Lead (Pb) exposure is associated with dental caries. Whether Pb affects tooth microhardness, is unclear. Our objective was to assess whether Pb concentration is associated with microhardness. Exfoliated primary teeth were collected from 46 volunteers. Teeth were sectioned, one half of each tooth was tested for enamel Knoop microhardness. The remaining half was digested and Pb measured using an inductively coupled plasma-mass spectrometer. The correlations between Pb levels and microhardness were very low, and were not statistically significant at p < 0.05. Previous exposure to high levels of Pb was not associated with decreased tooth microhardness. This study assessed whether Pb in deciduous teeth is associated with tooth microhardness. As this was not the case, further studies are needed to identify the mechanisms behind the association between lead exposure and tooth decay.

Identifiants

pubmed: 31049448
doi: 10.1016/j.heliyon.2019.e01551
pii: S2405-8440(18)35844-4
pii: e01551
pmc: PMC6484203
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e01551

Références

JAMA. 1999 Jun 23-30;281(24):2294-8
pubmed: 10386553
Oral Dis. 1999 Apr;5(2):100-3
pubmed: 10522204
Environ Health Perspect. 2000 Nov;108(11):1099-102
pubmed: 11102303
J Dent Educ. 2001 Oct;65(10):1046-53
pubmed: 11699976
Toxicology. 2002 Jun 14;175(1-3):27-34
pubmed: 12049833
Environ Health Perspect. 2002 Oct;110(10):A625-30
pubmed: 12361944
Sci Total Environ. 2006 May 15;361(1-3):88-96
pubmed: 15975635
Sci Total Environ. 2009 Feb 15;407(5):1547-50
pubmed: 19046759
Acad Pediatr. 2009 Nov-Dec;9(6):372-3
pubmed: 19945069
Arch Oral Biol. 2011 Jul;56(7):695-702
pubmed: 21269604
J Dent Res. 2012 Sep;91(9):865-70
pubmed: 22837551
J Perinatol. 2013 Oct;33(10):800-5
pubmed: 23807719
Springerplus. 2013 Oct 02;2:499
pubmed: 24133648
J Dent Res. 2015 Jan;94(1):19-26
pubmed: 25344336
Caries Res. 2015;49(1):26-33
pubmed: 25358243
NCHS Data Brief. 2015 Mar;(191):1-8
pubmed: 25932891
Pediatr Dent. 2015 Sep-Oct;37(5):462-7
pubmed: 26531091
BMC Oral Health. 2017 Jan 13;17(1):42
pubmed: 28086936
Nat Rev Dis Primers. 2017 May 25;3:17030
pubmed: 28540937

Auteurs

Betsy Foxman (B)

Center for Molecular and Clinical Epidemiology of Infectious Diseases, Department of Epidemiology, University of Michigan School of Public Health, 1415 Washington Heights, Ann Arbor, Michigan, 48109, USA.

Ethan Kolderman (E)

Center for Molecular and Clinical Epidemiology of Infectious Diseases, Department of Epidemiology, University of Michigan School of Public Health, 1415 Washington Heights, Ann Arbor, Michigan, 48109, USA.
University of Michigan School of Dentistry, 101 N. University Ave, Ann Arbor, Michigan, 48109, USA.

Elizabeth Salzman (E)

Center for Molecular and Clinical Epidemiology of Infectious Diseases, Department of Epidemiology, University of Michigan School of Public Health, 1415 Washington Heights, Ann Arbor, Michigan, 48109, USA.

Anna Cronenwett (A)

Center for Molecular and Clinical Epidemiology of Infectious Diseases, Department of Epidemiology, University of Michigan School of Public Health, 1415 Washington Heights, Ann Arbor, Michigan, 48109, USA.

Carlos Gonzalez-Cabezas (C)

Department of Cariology, Restorative Sciences and Endodontics, School of Dentistry, University of Michigan School of Dentistry, 101 N. University Ave, Ann Arbor, Michigan, 48109, USA.

Katherine Neiswanger (K)

Center for Craniofacial and Dental Genetics, Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, 3501 Terrace Street, Pittsburgh, Pennsylvania, 15261, USA.

Mary L Marazita (ML)

Center for Craniofacial and Dental Genetics, Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, 3501 Terrace Street, Pittsburgh, Pennsylvania, 15261, USA.
Department of Human Genetics, Graduate School of Public Health, Clinical and Translational Sciences Institute, School of Medicine University of Pittsburgh, 130 De Soto Street, Pittsburgh, Pennsylvania, 15261, USA.

Classifications MeSH