Comparison of Performance Characteristics of DxN VERIS System versus Qiagen PCR for HBV Genotype D and HCV Genotype 1b Quantification.


Journal

Polish journal of microbiology
ISSN: 2544-4646
Titre abrégé: Pol J Microbiol
Pays: Poland
ID NLM: 101229003

Informations de publication

Date de publication:
2019
Historique:
accepted: 14 11 2018
entrez: 4 5 2019
pubmed: 3 5 2019
medline: 1 6 2019
Statut: ppublish

Résumé

The Beckman Coulter DxN VERIS system is a fully automated, closed molecular diagnostic instrument for viral load quantification of hepatitis B virus and hepatitis C virus. In this study, the analytical performance of this new system was compared to routine diagnostic Qiagen PCR kit by using the same clinical samples. The DxN VERIS system demonstrated a high analytical performance. The DxN VERIS allows random access, which means that samples can be uploaded straight on to the system at any time; so, it provides an improvement of workflow, staff productivity and allows faster turn-around of viral load results. The Beckman Coulter DxN VERIS system is a fully automated, closed molecular diagnostic instrument for viral load quantification of hepatitis B virus and hepatitis C virus. In this study, the analytical performance of this new system was compared to routine diagnostic Qiagen PCR kit by using the same clinical samples. The DxN VERIS system demonstrated a high analytical performance. The DxN VERIS allows random access, which means that samples can be uploaded straight on to the system at any time; so, it provides an improvement of workflow, staff productivity and allows faster turn-around of viral load results.

Identifiants

pubmed: 31050262
doi: 10.21307/pjm-2019-008
pii: exeley
pmc: PMC7256835
doi:

Substances chimiques

RNA, Viral 0

Types de publication

Comparative Study Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

139-143

Références

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pubmed: 28306597
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pubmed: 27667367
J Clin Virol. 2017 May;90:18-25
pubmed: 28319847
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pubmed: 29642827
World J Gastroenterol. 2014 Oct 28;20(40):14559-67
pubmed: 25356020
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pubmed: 30215235
Int J Appl Basic Med Res. 2017 Jan-Mar;7(1):3-9
pubmed: 28251100
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pubmed: 28427875
J Clin Virol. 2016 Nov;84:7-11
pubmed: 27636506
PLoS One. 2017 Feb 9;12(2):e0170290
pubmed: 28182626

Auteurs

Murat Sayan (M)

Kocaeli University, Faculty of Medicine, Clinical Laboratory, PCR Unit , Kocaeli , Turkey ; Near East University, Research Center of Experimental Health Sciences , Nicosia , Northern Cyprus.

Ayse Arikan (A)

Near East University, Research Center of Experimental Health Sciences , Nicosia , Northern Cyprus ; Near East University, Faculty of Medicine, Department of Medical Microbiology , Nicosia , Northern Cyprus.

Tamer Sanlidag (T)

Near East University, Research Center of Experimental Health Sciences , Nicosia , Northern Cyprus ; Celal Bayar University, Faculty of Medicine, Department of Medical Microbiology , Manisa , Turkey.

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Classifications MeSH