Pharmacogenomics in dermatology: tools for understanding gene-drug associations.
Journal
Seminars in cutaneous medicine and surgery
ISSN: 1558-0768
Titre abrégé: Semin Cutan Med Surg
Pays: United States
ID NLM: 9617260
Informations de publication
Date de publication:
01 Mar 2019
01 Mar 2019
Historique:
entrez:
4
5
2019
pubmed:
6
5
2019
medline:
18
12
2019
Statut:
epublish
Résumé
Pharmacogenomics aims to associate human genetic variability with differences in drug phenotypes in order to tailor drug treatment to individual patients. The massive amount of genetic data generated from large cohorts of patients with variable drug phenotypes have led to advances in this field. Understanding the application of pharmacogenomics in dermatology could inform clinical practice and provide insight for future research. The Pharmacogenomics Knowledge Base and the Clinical Pharmacogenetics Implementation Consortium are among the resources to help clinicians and researchers navigate the many gene-drug associations that have already been discovered. The implementation of clinical pharmacogenomics within health care systems remains an area of ongoing development. This review provides an introduction to the field of pharmacogenomics and to current pharmacogenomics resources using examples of gene-drug associations relevant to the field of dermatology.
Identifiants
pubmed: 31051019
doi: 10.12788/j.sder.2019.009
pmc: PMC6681802
mid: NIHMS1040668
doi:
Substances chimiques
Dermatologic Agents
0
Types de publication
Journal Article
Review
Langues
eng
Pagination
E19-E24Subventions
Organisme : NIGMS NIH HHS
ID : R24 GM061374
Pays : United States
Informations de copyright
©2019 Frontline Medical Communications.
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