XPO1 expression
pancreas cancer
prognosis
survival
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
30 Apr 2019
30 Apr 2019
Historique:
received:
01
04
2019
revised:
26
04
2019
accepted:
28
04
2019
entrez:
5
5
2019
pubmed:
6
5
2019
medline:
6
5
2019
Statut:
epublish
Résumé
Pancreatic adenocarcinoma (PAC) is one of the most aggressive human cancers and new systemic therapies are urgently needed. Exportin-1 (XPO1), which is a member of the importin-β superfamily of karyopherins, is the major exporter of many tumor suppressor proteins that are involved in the progression of PAC. Promising pre-clinical data using XPO1 inhibitors have been reported in PAC, but very few data are available regarding XPO1 expression in clinical samples. Retrospectively, we analyzed
Identifiants
pubmed: 31052304
pii: jcm8050596
doi: 10.3390/jcm8050596
pmc: PMC6572621
pii:
doi:
Types de publication
Journal Article
Langues
eng
Déclaration de conflit d'intérêts
The authors have no conflict of interest to declare.
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