A New Analytical Method for Determination of Cathepsin L Based on the Surface Plasmon Resonance Imaging Biosensor.
Surface Plasmon Resonance Imaging technique
biosensors
cathepsin L
endopeptidase
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
01 May 2019
01 May 2019
Historique:
received:
02
04
2019
revised:
25
04
2019
accepted:
30
04
2019
entrez:
5
5
2019
pubmed:
6
5
2019
medline:
14
8
2019
Statut:
epublish
Résumé
The purpose of this study was to develop a new method for a determination of the cathepsin L-biosensor based on the Surface Plasmon Resonance Imaging technique. The cathepsin L is an endopeptidase, which degrades proteins and plays an important role in various processes occurring in the human body. The detection technique, Surface Plasmon Resonance Imaging, is an optical, label-free technique, which can be used for quantitative determination of the different proteins. In order to bind the enzyme, the cathepsin L inhibitor-RKLLW-NH
Identifiants
pubmed: 31052424
pii: ijms20092166
doi: 10.3390/ijms20092166
pmc: PMC6539348
pii:
doi:
Substances chimiques
Cathepsin L
EC 3.4.22.15
Types de publication
Journal Article
Langues
eng
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