Synthesis and Anticancer Activity of Novel 9-
EPR spectroscopy
antitumor activity
apoptosis
berberine
berberine derivatives
cell cycle arrest
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
01 May 2019
01 May 2019
Historique:
received:
11
04
2019
revised:
25
04
2019
accepted:
30
04
2019
entrez:
5
5
2019
pubmed:
6
5
2019
medline:
14
8
2019
Statut:
epublish
Résumé
Berberine is a bioactive isoquinoline alkaloid derived from many plants. Although berberine has been shown to inhibit growth and induce apoptosis of several tumor cell lines, its poor absorption and moderate activity hamper its full therapeutic potential. Here, we describe the synthesis of a series of 9-
Identifiants
pubmed: 31052469
pii: ijms20092169
doi: 10.3390/ijms20092169
pmc: PMC6539820
pii:
doi:
Substances chimiques
Antineoplastic Agents
0
Berberine
0I8Y3P32UF
Types de publication
Journal Article
Langues
eng
Déclaration de conflit d'intérêts
The authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.
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