Data-Driven UPLC-Orbitrap MS Analysis in Astrochemistry.
astrochemistry
data analysis
high-resolving analytical chemistry
meteorites
origin of life
Journal
Life (Basel, Switzerland)
ISSN: 2075-1729
Titre abrégé: Life (Basel)
Pays: Switzerland
ID NLM: 101580444
Informations de publication
Date de publication:
02 May 2019
02 May 2019
Historique:
received:
30
03
2019
revised:
13
04
2019
accepted:
23
04
2019
entrez:
5
5
2019
pubmed:
6
5
2019
medline:
6
5
2019
Statut:
epublish
Résumé
Meteorites have been found to be rich and highly diverse in organic compounds. Next to previous direct infusion high resolution mass spectrometry experiments (DI-HR-MS), we present here data-driven strategies to evaluate UPLC-Orbitrap MS analyses. This allows a comprehensive mining of structural isomers extending the level of information on the molecular diversity in astrochemical materials. As a proof-of-concept study, Murchison and Allende meteorites were analyzed. Both, global organic fingerprint and specific isomer analyses are discussed. Up to 31 different isomers per molecular composition are present in Murchison suggesting the presence of ≈440,000 different compounds detected therein. By means of this time-resolving high resolution mass spectrometric method, we go one step further toward the characterization of chemical structures within complex extraterrestrial mixtures, enabling a better understanding of organic chemical evolution, from interstellar ices toward small bodies in the Solar System.
Identifiants
pubmed: 31052536
pii: life9020035
doi: 10.3390/life9020035
pmc: PMC6617268
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : ANR
ID : ANR-16-CE29-0015
Organisme : CNES
ID : CNES, R-S18/SU-0003-072
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