Decompressive Craniectomy in Children with Severe Traumatic Brain Injury: A Multicenter Retrospective Study and Literature Review.


Journal

World neurosurgery
ISSN: 1878-8769
Titre abrégé: World Neurosurg
Pays: United States
ID NLM: 101528275

Informations de publication

Date de publication:
Sep 2019
Historique:
received: 07 03 2019
revised: 23 04 2019
accepted: 24 04 2019
pubmed: 6 5 2019
medline: 21 1 2020
entrez: 5 5 2019
Statut: ppublish

Résumé

Severe traumatic brain injury (TBI) is the most common cause of disability in children. Refractory increased intracranial pressure can be a therapeutic challenge. Decompressive craniectomy can be proposed when medical management is insufficient, but its place is not clearly defined in guidelines. The aim of this study was to identify prognostic factors in children with TBI. We performed a retrospective, multicenter study to analyze long-term outcomes of 150 children with severe TBI treated by decompressive craniectomy and to identify prognostic factors. A satisfactory neurologic evolution (represented by a King's Outcome Scale for Childhood Head Injury score >3) was observed in 62% of children with a mean follow-up of 3.5 years. Mortality rate was 17%. Prognostic factors associated with outcome were age, initial Glasgow Coma Scale score, presence of mydriasis, neuromonitoring values (maximal intracranial pressure >30 mm Hg), and radiologic findings (Rotterdam score ≥4). This study in a large population confirms that children with severe TBI treated by decompressive craniectomy can achieve a good neurologic outcome. Further studies are needed to clarify the use of this surgery in the management of children with severe TBI.

Sections du résumé

BACKGROUND BACKGROUND
Severe traumatic brain injury (TBI) is the most common cause of disability in children. Refractory increased intracranial pressure can be a therapeutic challenge. Decompressive craniectomy can be proposed when medical management is insufficient, but its place is not clearly defined in guidelines. The aim of this study was to identify prognostic factors in children with TBI.
METHODS METHODS
We performed a retrospective, multicenter study to analyze long-term outcomes of 150 children with severe TBI treated by decompressive craniectomy and to identify prognostic factors.
RESULTS RESULTS
A satisfactory neurologic evolution (represented by a King's Outcome Scale for Childhood Head Injury score >3) was observed in 62% of children with a mean follow-up of 3.5 years. Mortality rate was 17%. Prognostic factors associated with outcome were age, initial Glasgow Coma Scale score, presence of mydriasis, neuromonitoring values (maximal intracranial pressure >30 mm Hg), and radiologic findings (Rotterdam score ≥4).
CONCLUSIONS CONCLUSIONS
This study in a large population confirms that children with severe TBI treated by decompressive craniectomy can achieve a good neurologic outcome. Further studies are needed to clarify the use of this surgery in the management of children with severe TBI.

Identifiants

pubmed: 31054345
pii: S1878-8750(19)31211-2
doi: 10.1016/j.wneu.2019.04.215
pii:
doi:

Types de publication

Journal Article Multicenter Study Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

e56-e62

Informations de copyright

Copyright © 2019 Elsevier Inc. All rights reserved.

Auteurs

Marie Manfiotto (M)

Service de Neurochirurgie, CHU de Nice, Nice, France. Electronic address: marie.manfiotto@hotmail.com.

Kevin Beccaria (K)

Service de Neurochirurgie Pédiatrique, Hôpital Necker, Paris, France.

Alice Rolland (A)

Service de Neurochirurgie, CHU de Montpellier, Montpellier, France.

Giovanna Paternoster (G)

Service de Neurochirurgie Pédiatrique, Hôpital Necker, Paris, France.

Benjamin Plas (B)

Service de Neurochirurgie, CHU de Toulouse, Toulouse, France.

Sergio Boetto (S)

Service de Neurochirurgie, CHU de Toulouse, Toulouse, France.

Mathieu Vinchon (M)

Service de Neurochirurgie, CHU de Lille, Lille, France.

Carmine Mottolese (C)

Service de Neurochirurgie Pédiatrique, Hôpital Femme Mère Enfant, Lyon, France.

Pierre-Aurélien Beuriat (PA)

Service de Neurochirurgie Pédiatrique, Hôpital Femme Mère Enfant, Lyon, France.

Alexandru Szathmari (A)

Service de Neurochirurgie Pédiatrique, Hôpital Femme Mère Enfant, Lyon, France.

Federico Di Rocco (F)

Service de Neurochirurgie Pédiatrique, Hôpital Femme Mère Enfant, Lyon, France.

Didier Scavarda (D)

Service de Neurochirurgie Pédiatrique, Hôpital Timone, Marseille, France.

Eric Seigneuret (E)

Service de Neurochirurgie Pédiatrique, CHU Grenoble, Grenoble, France.

Isabelle Wrobleski (I)

Service de Neurochirurgie Pédiatrique, CHU Grenoble, Grenoble, France.

Olivier Klein (O)

Service de Neurochirurgie Pédiatrique, CHU Nancy, Nancy, France.

Antony Joud (A)

Service de Neurochirurgie Pédiatrique, CHU Nancy, Nancy, France.

Edouard Gimbert (E)

Service de Neurochirurgie Pédiatrique, CHU Bordeaux, Bordeaux, France.

Vincent Jecko (V)

Service de Neurochirurgie Pédiatrique, CHU Bordeaux, Bordeaux, France.

Jean Rodolphe Vignes (JR)

Service de Neurochirurgie Pédiatrique, CHU Bordeaux, Bordeaux, France.

Thomas Roujeau (T)

Service de Neurochirurgie, CHU de Montpellier, Montpellier, France.

Audrey Dupont (A)

Service de Réanimation Pédiatrique, Hôpital Lenval, Nice, France.

Michel Zerah (M)

Service de Neurochirurgie Pédiatrique, Hôpital Necker, Paris, France.

Michel Lonjon (M)

Service de Neurochirurgie, CHU de Nice, Nice, France.

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Classifications MeSH