Biosynthetic reconstitution of deoxysugar phosphoramidate metalloprotease inhibitors using an N-P-bond-forming kinase.


Journal

Chemical science
ISSN: 2041-6520
Titre abrégé: Chem Sci
Pays: England
ID NLM: 101545951

Informations de publication

Date de publication:
28 Apr 2019
Historique:
received: 05 02 2019
accepted: 11 03 2019
entrez: 7 5 2019
pubmed: 7 5 2019
medline: 7 5 2019
Statut: epublish

Résumé

Phosphoramidon is a potent metalloprotease inhibitor and a widespread tool in cell biology research. It contains a dipeptide backbone that is uniquely linked to a 6-deoxysugar

Identifiants

pubmed: 31057776
doi: 10.1039/c9sc00641a
pii: c9sc00641a
pmc: PMC6482885
doi:

Types de publication

Journal Article

Langues

eng

Pagination

4486-4490

Références

J Mol Biol. 2002 Jul 19;320(4):855-81
pubmed: 12095261
Angew Chem Int Ed Engl. 2004 May 24;43(22):2962-5
pubmed: 15170316
Exp Neurol. 2005 Sep;195(1):179-84
pubmed: 15963503
Mol Microbiol. 2005 Oct;58(1):17-27
pubmed: 16164546
Proc Natl Acad Sci U S A. 2006 Jun 6;103(23):8846-51
pubmed: 16731618
J Bacteriol. 2007 Apr;189(7):2834-43
pubmed: 17237165
J Am Chem Soc. 2008 Mar 19;130(11):3603-9
pubmed: 18290647
Curr Opin Chem Biol. 2008 Jun;12(3):292-6
pubmed: 18423417
J Biol Chem. 2009 May 29;284(22):14987-96
pubmed: 19351877
Biochemistry. 2009 Sep 22;48(37):8830-41
pubmed: 19640006
ChemMedChem. 2009 Nov;4(11):1779-91
pubmed: 19760699
Appl Environ Microbiol. 2010 Jun;76(12):4008-18
pubmed: 20418426
Nat Chem Biol. 2011 Feb;7(2):78-80
pubmed: 21196935
Nat Prod Rep. 2011 Oct;28(11):1811-53
pubmed: 21901218
Angew Chem Int Ed Engl. 2014 Jan 27;53(5):1334-7
pubmed: 24376039
Chem Soc Rev. 2015 Nov 7;44(21):7591-697
pubmed: 25735878
Angew Chem Int Ed Engl. 2017 Feb 13;56(8):2026-2029
pubmed: 28097768
Curr Opin Cell Biol. 2017 Apr;45:8-16
pubmed: 28129587
Chem Rev. 2017 Apr 26;117(8):5784-5863
pubmed: 28375000
Angew Chem Int Ed Engl. 2017 Jun 1;56(23):6665-6668
pubmed: 28452105
Chemistry. 2017 Aug 10;23(45):10714-10724
pubmed: 28488371
J Am Chem Soc. 2017 Jul 19;139(28):9463-9466
pubmed: 28650156
Nat Commun. 2017 Dec 6;8(1):1965
pubmed: 29213087
Biochemistry. 2018 Sep 18;57(37):5447-5455
pubmed: 30142271
J Bacteriol. 1986 Dec;168(3):1384-91
pubmed: 3536876
Eur J Biochem. 1986 Jun 2;157(2):261-8
pubmed: 3709536
Proc Natl Acad Sci U S A. 1968 Dec;61(4):1448-53
pubmed: 4303480
J Antibiot (Tokyo). 1973 Oct;26(10):621-3
pubmed: 4792110
Thorax. 1995 May;50(5):505-10
pubmed: 7597662
J Bacteriol. 1995 Dec;177(24):7131-40
pubmed: 8522520
Proc Natl Acad Sci U S A. 1996 Apr 2;93(7):2652-7
pubmed: 8610096
Circulation. 1996 Nov 1;94(9):2131-7
pubmed: 8901663
J Mol Biol. 1977 Jul;114(1):119-32
pubmed: 909082

Auteurs

Alexandra Baulig (A)

Department of Pharmaceutical Biology , Pharmaceutical Institute , University of Tübingen , 72076 Tübingen , Germany . Email: leonard.kaysser@uni-tuebingen.de.
German Centre for Infection Research (DZIF) , partner site Tübingen , 72076 Tübingen , Germany.

Irina Helmle (I)

Department of Pharmaceutical Biology , Pharmaceutical Institute , University of Tübingen , 72076 Tübingen , Germany . Email: leonard.kaysser@uni-tuebingen.de.

Marius Bader (M)

Department of Pharmaceutical Biology , Pharmaceutical Institute , University of Tübingen , 72076 Tübingen , Germany . Email: leonard.kaysser@uni-tuebingen.de.
German Centre for Infection Research (DZIF) , partner site Tübingen , 72076 Tübingen , Germany.

Felix Wolf (F)

Department of Pharmaceutical Biology , Pharmaceutical Institute , University of Tübingen , 72076 Tübingen , Germany . Email: leonard.kaysser@uni-tuebingen.de.
German Centre for Infection Research (DZIF) , partner site Tübingen , 72076 Tübingen , Germany.

Andreas Kulik (A)

Interfaculty Institute for Microbiology and Infection Medicine Tübingen (IMIT) , Microbiology/Biotechnology , University of Tübingen , 72076 Tübingen , Germany.

Arwa Al-Dilaimi (A)

Center for Biotechnology (CeBiTec) , Bielefeld University , 33615 Bielefeld , Germany.

Daniel Wibberg (D)

Center for Biotechnology (CeBiTec) , Bielefeld University , 33615 Bielefeld , Germany.

Jörn Kalinowski (J)

Center for Biotechnology (CeBiTec) , Bielefeld University , 33615 Bielefeld , Germany.

Harald Gross (H)

Department of Pharmaceutical Biology , Pharmaceutical Institute , University of Tübingen , 72076 Tübingen , Germany . Email: leonard.kaysser@uni-tuebingen.de.
German Centre for Infection Research (DZIF) , partner site Tübingen , 72076 Tübingen , Germany.

Leonard Kaysser (L)

Department of Pharmaceutical Biology , Pharmaceutical Institute , University of Tübingen , 72076 Tübingen , Germany . Email: leonard.kaysser@uni-tuebingen.de.
German Centre for Infection Research (DZIF) , partner site Tübingen , 72076 Tübingen , Germany.

Classifications MeSH