Risk factors for fragility fractures in type 1 diabetes.
Complications
Fractures
Glucose control
Risk factors
Type 1 diabetes
Journal
Bone
ISSN: 1873-2763
Titre abrégé: Bone
Pays: United States
ID NLM: 8504048
Informations de publication
Date de publication:
08 2019
08 2019
Historique:
received:
03
12
2018
revised:
17
04
2019
accepted:
24
04
2019
pubmed:
7
5
2019
medline:
4
8
2020
entrez:
7
5
2019
Statut:
ppublish
Résumé
To determine clinical diabetes-related risk factors for fragility fractures in type 1 diabetes (T1D). History of bone fragility fractures occurring after T1D diagnosis was assessed by questionnaire in this cross-sectional study in 600 T1D subjects. Glycated hemoglobin A1c (HbA1c) over the previous 5 years was used as an index of long-term glycemic control; complications were adjudicated by physician assessment. Multinomial logistic regression models were used to assess the associations between diabetes-related risk factors and fracture history. One-hundred-eleven patients (18.5%) reported at least one fracture; of these 73.8% had only one and 26.2% had more than one fracture. Average age was 41.9 ± 12.8 years, with even gender distribution; disease duration was 19.9 ± 12.0 years; and BMI was 24.4 ± 3.7 kg/m Poor glycemic control and long exposure to the disease are independent diabetes-related risk factors for multiple bone fractures in T1D.
Identifiants
pubmed: 31059862
pii: S8756-3282(19)30153-X
doi: 10.1016/j.bone.2019.04.017
pii:
doi:
Substances chimiques
Blood Glucose
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
194-199Commentaires et corrections
Type : CommentIn
Type : CommentIn
Informations de copyright
Copyright © 2019 Elsevier Inc. All rights reserved.