Thromboembolism in the Absence of Atrial Fibrillation.

Anticoagulants / therapeutic use Atrial Appendage / diagnostic imaging Atrial Fibrillation Atrial Function, Left / physiology Echocardiography, Transesophageal Humans Prognosis Risk Factors Thromboembolism / diagnosis

Journal

The American journal of cardiology
ISSN: 1879-1913
Titre abrégé: Am J Cardiol
Pays: United States
ID NLM: 0207277

Informations de publication

Date de publication:
15 07 2019
Historique:
received: 18 01 2019
revised: 30 03 2019
accepted: 04 04 2019
pubmed: 8 5 2019
medline: 23 2 2020
entrez: 8 5 2019
Statut: ppublish

Résumé

Atrial fibrillation (AF) is associated with thrombus formation in the left atrial appendage and systemic embolic events including ischemic stroke. Cardiogenic thromboembolism can also occur in the absence of clinical AF as a result of various pathological conditions affecting the endocardium. The inconsistent temporal relation between AF and ischemic events has stimulated exploration for factors other than clinical AF that contribute to thromboembolism. These include subclinical AF, a thrombogenic atrial cardiomyopathy, and left atrial appendage dysfunction and embolism from other sources. In conclusion, thromboembolism during normal sinus rhythm is likely multifactorial, involving intertwined pathologic processes. Patients at risk, if accurately identified, could theoretically benefit from anticoagulation.

Identifiants

DOI: 10.1016/j.amjcard.2019.04.027 PMID: 31060729
pubmed: 31060729
pii: S0002-9149(19)30466-7
doi: 10.1016/j.amjcard.2019.04.027
pii:
doi:

Substances chimiques

Anticoagulants 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

303-311

Commentaires et corrections

Type : CommentIn
Type : CommentIn

Informations de copyright

Copyright © 2019 Elsevier Inc. All rights reserved.

Auteurs

Jeffrey Smietana (J)

The Cardiovascular Institute, Mount Sinai Medical Center, New York, New York.

Anna Plitt (A)

The Cardiovascular Institute, Mount Sinai Medical Center, New York, New York.

Jonathan L Halperin (JL)

The Cardiovascular Institute, Mount Sinai Medical Center, New York, New York. Electronic address: jonathan.halperin@mssm.edu.

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Agents hématologiques › Anticoagulants › Thromboembolism in the Absence of Atrial Fibrillation.
questionsmedicales.fr › Système cardiovasculaire › Coeur › Atrium du coeur › Auricule de l'atrium › Thromboembolism in the Absence of Atrial Fibrillation.
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Troubles du rythme cardiaque › Fibrillation auriculaire › Thromboembolism in the Absence of Atrial Fibrillation.
questionsmedicales.fr › Phénomènes physiologiques respiratoires et circulatoires › Phénomènes physiologiques cardiovasculaires › Fonction auriculaire › Fonction auriculaire gauche › Thromboembolism in the Absence of Atrial Fibrillation.
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Techniques de diagnostic cardiovasculaire › Tests de la fonction cardiaque › Échocardiographie › Échocardiographie transoesophagienne › Thromboembolism in the Absence of Atrial Fibrillation.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Thromboembolism in the Absence of Atrial Fibrillation.
questionsmedicales.fr › Diagnostic › Pronostic › Thromboembolism in the Absence of Atrial Fibrillation.
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Statistiques comme sujet › Probabilité › Risque › Facteurs de risque › Thromboembolism in the Absence of Atrial Fibrillation.
questionsmedicales.fr › Maladies cardiovasculaires › Maladies vasculaires › Embolie et thrombose › Thromboembolie › Thromboembolism in the Absence of Atrial Fibrillation.