Brain ventricular volume changes induced by long-duration spaceflight.


Journal

Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876

Informations de publication

Date de publication:
21 05 2019
Historique:
pubmed: 8 5 2019
medline: 31 3 2020
entrez: 8 5 2019
Statut: ppublish

Résumé

Long-duration spaceflight induces detrimental changes in human physiology. Its residual effects and mechanisms remain unclear. We prospectively investigated the changes in cerebrospinal fluid (CSF) volume of the brain ventricular regions in space crew by means of a region of interest analysis on structural brain scans. Cosmonaut MRI data were investigated preflight (

Identifiants

pubmed: 31061119
pii: 1820354116
doi: 10.1073/pnas.1820354116
pmc: PMC6535034
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

10531-10536

Commentaires et corrections

Type : CommentIn
Type : CommentIn
Type : CommentIn
Type : CommentIn

Informations de copyright

Copyright © 2019 the Author(s). Published by PNAS.

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

Références

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Auteurs

Angelique Van Ombergen (A)

Lab for Equilibrium Investigations and Aerospace, University of Antwerp, 2610 Antwerp, Belgium; angelique.vanombergen@uantwerpen.be.
Department of Translational Neurosciences, University of Antwerp, 2610 Antwerp, Belgium.

Steven Jillings (S)

Lab for Equilibrium Investigations and Aerospace, University of Antwerp, 2610 Antwerp, Belgium.
Coma Science Group, GIGA Research, Neurology Department, University and University Hospital of Liège, 4000 Liège, Belgium.

Ben Jeurissen (B)

Imec/Vision Lab, University of Antwerp, 2610 Antwerp, Belgium.

Elena Tomilovskaya (E)

State Science Center of the Russian Federation, Institute of Biomedical Problems, Russian Academy of Sciences, 123007 Moscow, Russia.

Alena Rumshiskaya (A)

Radiology Department, Federal Center of Treatment and Rehabilitation, 125367 Moscow, Russia.

Liudmila Litvinova (L)

Radiology Department, Federal Center of Treatment and Rehabilitation, 125367 Moscow, Russia.

Inna Nosikova (I)

State Science Center of the Russian Federation, Institute of Biomedical Problems, Russian Academy of Sciences, 123007 Moscow, Russia.

Ekaterina Pechenkova (E)

Laboratory for Cognitive Research, National Research University, Higher School of Economics, 101000 Moscow, Russia.

Ilya Rukavishnikov (I)

State Science Center of the Russian Federation, Institute of Biomedical Problems, Russian Academy of Sciences, 123007 Moscow, Russia.

Olga Manko (O)

State Science Center of the Russian Federation, Institute of Biomedical Problems, Russian Academy of Sciences, 123007 Moscow, Russia.

Sergey Danylichev (S)

Gagarin Cosmonauts Training Center, 141160 Star City, Russia.

R Maxine Rühl (RM)

Department of Neurology, Ludwig-Maximilians-University Munich, 81377 Munich, Germany.

Inessa B Kozlovskaya (IB)

State Science Center of the Russian Federation, Institute of Biomedical Problems, Russian Academy of Sciences, 123007 Moscow, Russia.

Stefan Sunaert (S)

Translational MRI, Department of Imaging & Pathology, Katholieke Universiteit Leuven, 3000 Leuven, Belgium.

Paul M Parizel (PM)

Radiology Department, Antwerp University Hospital and University of Antwerp, 2650 Antwerp, Belgium.

Valentin Sinitsyn (V)

Faculty of Fundamental Medicine, Lomonosov Moscow State University, 119991 Moscow, Russia.

Steven Laureys (S)

Coma Science Group, GIGA Research, Neurology Department, University and University Hospital of Liège, 4000 Liège, Belgium.

Jan Sijbers (J)

Imec/Vision Lab, University of Antwerp, 2610 Antwerp, Belgium.

Peter Zu Eulenburg (P)

Department of Neurology, Ludwig-Maximilians-University Munich, 81377 Munich, Germany.

Floris L Wuyts (FL)

Lab for Equilibrium Investigations and Aerospace, University of Antwerp, 2610 Antwerp, Belgium.

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