Urinary Uromodulin Levels and


Journal

International journal of nephrology
ISSN: 2090-214X
Titre abrégé: Int J Nephrol
Pays: United States
ID NLM: 101546753

Informations de publication

Date de publication:
2019
Historique:
received: 11 12 2018
revised: 27 02 2019
accepted: 03 03 2019
entrez: 9 5 2019
pubmed: 9 5 2019
medline: 9 5 2019
Statut: epublish

Résumé

Uromodulin, the most abundant protein in urine, is synthesized in the thick ascending loop of Henle and distal convoluted tubules. Patients with chronic kidney disease (CKD) have reduced urinary uromodulin levels secondary to tubular damage. Genome wide association studies identified significant single nucleotide polymorphism (SNP) associations with CKD at the uromodulin (

Identifiants

pubmed: 31065383
doi: 10.1155/2019/8094049
pmc: PMC6466913
doi:

Types de publication

Journal Article

Langues

eng

Pagination

8094049

Références

Immunol Cell Biol. 2000 Oct;78(5):474-82
pubmed: 11050529
J Biol Chem. 2001 Mar 30;276(13):9924-30
pubmed: 11134021
J Med Genet. 2002 Dec;39(12):882-92
pubmed: 12471200
Am J Kidney Dis. 2003 Oct;42(4):658-76
pubmed: 14520616
Kidney Int. 2004 Mar;65(3):791-7
pubmed: 14871399
J Exp Med. 1952 Jan;95(1):71-97
pubmed: 14907962
Kidney Int. 2004 Sep;66(3):1159-66
pubmed: 15327412
Scand J Urol Nephrol. 2008;42(2):168-74
pubmed: 17907053
Curr Opin Nephrol Hypertens. 2008 May;17(3):258-65
pubmed: 18408476
Am J Physiol Renal Physiol. 2008 Aug;295(2):F534-44
pubmed: 18495803
J Hypertens. 2009 Mar;27(3):606-12
pubmed: 19262228
Ann Intern Med. 2009 May 5;150(9):604-12
pubmed: 19414839
Nat Genet. 2009 Jun;41(6):712-7
pubmed: 19430482
J Am Soc Nephrol. 2010 Feb;21(2):337-44
pubmed: 19959715
Nephrol Dial Transplant. 2010 Jun;25(6):1896-903
pubmed: 20075439
PLoS Genet. 2010 Jul 29;6(7):e1001039
pubmed: 20686651
J Biol Chem. 2011 Jan 21;286(3):2224-35
pubmed: 21081491
PLoS Genet. 2010 Oct 28;6(10):e1001177
pubmed: 21082022
Kidney Int. 2011 Aug;80(4):338-47
pubmed: 21654721
J Biol Chem. 2011 Aug 26;286(34):30200-10
pubmed: 21737451
PLoS One. 2013 Aug 22;8(8):e71023
pubmed: 23990922
Science. 1985 Aug 2;229(4712):479-81
pubmed: 2409603
Hypertension. 2014 Mar;63(3):551-8
pubmed: 24324041
Clin J Am Soc Nephrol. 2016 Jan 7;11(1):70-80
pubmed: 26683888
Kidney Int. 2018 Oct;94(4):701-715
pubmed: 30007527
Clin J Am Soc Nephrol. 2018 Oct 8;13(10):1556-1557
pubmed: 30054352
Am J Hypertens. 1988 Oct;1(4 Pt 1):335-47
pubmed: 3063284
Nucleic Acids Res. 1988 Feb 11;16(3):1215
pubmed: 3344216
Science. 1987 Apr 3;236(4797):83-8
pubmed: 3453112
Science. 1987 Sep 18;237(4821):1479-84
pubmed: 3498215
Clin Nephrol. 1984 Nov;22(5):253-7
pubmed: 6518675
Nephron. 1993;65(2):227-31
pubmed: 8247185
Kidney Int. 1993 Nov;44(5):1014-21
pubmed: 8264130
Control Clin Trials. 1996 Aug;17(4 Suppl):3S-16S
pubmed: 8889350
Br J Urol. 1998 Jan;81(1):14-9
pubmed: 9467470
Kidney Int. 1998 Oct;54(4):1150-6
pubmed: 9767530

Auteurs

Nolubabalo Unati Nqebelele (NU)

Department of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Caroline Dickens (C)

Department of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Therese Dix-Peek (T)

Department of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Raquel Duarte (R)

Department of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Saraladevi Naicker (S)

Department of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Classifications MeSH