Risk scoring system for predicting breast conservation after neoadjuvant chemotherapy.
breast conservation
neoadjuvant chemotherapy
risk scoring system
Journal
The breast journal
ISSN: 1524-4741
Titre abrégé: Breast J
Pays: United States
ID NLM: 9505539
Informations de publication
Date de publication:
07 2019
07 2019
Historique:
received:
10
02
2018
revised:
06
09
2018
accepted:
10
09
2018
pubmed:
9
5
2019
medline:
15
1
2020
entrez:
9
5
2019
Statut:
ppublish
Résumé
We developed a risk scoring system (RSS) for predicting breast conservative surgery (BCS) in women receiving neoadjuvant chemotherapy(NAC) for breast cancer. BCS rate in the training set was 32.6%, associated with five variables: age < 50years, primary radiological tumor diameter < 60mm, absence of multifocality, absence of breast inflammation and hormone receptor status. These variables were assigned scores ranging from 0 to 9. The discrimination of the RSS was 0.78(95%CI 0.69-0.86) in the training set. The area under the curve of the receiver operating characteristics for predicting BCS after internal and external validation was 0.77(95%CI 0.68-0.85) and 0.75(95%CI 0.66-0.84), respectively.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
696-701Informations de copyright
© 2019 Wiley Periodicals, Inc.