Critical Evaluation of Sinonasal Disease in 64 Adults with Primary Ciliary Dyskinesia.
Kartagener syndrome
airway mucociliary clearance
chronic rhinosinusitis
otitis media with effusion
primary ciliary dyskinesia
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
07 May 2019
07 May 2019
Historique:
received:
14
03
2019
revised:
23
04
2019
accepted:
01
05
2019
entrez:
10
5
2019
pubmed:
10
5
2019
medline:
10
5
2019
Statut:
epublish
Résumé
To date, no study precisely described ear, nose and throat (ENT) disease in adults with primary ciliary dyskinesia (PCD) and its relationship with ciliary function/ultrastructure. A retrospective study of standardized ENT data (exam, audiogram, sinus Computed tomography (CT), and bacteriology) was conducted in 64 adults with confirmed PCD who were followed in two ENT reference centers. Rhinorrhoea and hearing loss were the main symptoms. Symptom scores were higher in older patients. Nasal endoscopy was abnormal in all patients except one, showing nasal polyps in one-third of the patients and stagnant nasal mucus secretions in 87.5% of the patients. Sinus CT opacities were mainly incomplete and showed one-third of the patients with sinus hypoplasia and/or agenesis. Middle meatus mainly grew
Identifiants
pubmed: 31067752
pii: jcm8050619
doi: 10.3390/jcm8050619
pmc: PMC6571605
pii:
doi:
Types de publication
Journal Article
Langues
eng
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