MicroRNA therapy stimulates uncontrolled cardiac repair after myocardial infarction in pigs.


Journal

Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462

Informations de publication

Date de publication:
05 2019
Historique:
received: 20 03 2018
accepted: 09 04 2019
pubmed: 10 5 2019
medline: 13 2 2020
entrez: 10 5 2019
Statut: ppublish

Résumé

Prompt coronary catheterization and revascularization have markedly improved the outcomes of myocardial infarction, but have also resulted in a growing number of surviving patients with permanent structural damage of the heart, which frequently leads to heart failure. There is an unmet clinical need for treatments for this condition

Identifiants

pubmed: 31068698
doi: 10.1038/s41586-019-1191-6
pii: 10.1038/s41586-019-1191-6
pmc: PMC6768803
mid: EMS82584
doi:

Substances chimiques

MicroRNAs 0
mirn199 microRNA, human 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

418-422

Subventions

Organisme : European Research Council
ID : 787971
Pays : International

Commentaires et corrections

Type : CommentIn

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Auteurs

Khatia Gabisonia (K)

Institute of Life Sciences, Scuola Superiore Sant'Anna, Pisa, Italy.

Giulia Prosdocimo (G)

Molecular Medicine Laboratory, International Centre for Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy.

Giovanni Donato Aquaro (GD)

Fondazione Toscana Gabriele Monasterio, Pisa, Italy.

Lucia Carlucci (L)

Institute of Life Sciences, Scuola Superiore Sant'Anna, Pisa, Italy.

Lorena Zentilin (L)

Molecular Medicine Laboratory, International Centre for Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy.

Ilaria Secco (I)

Molecular Medicine Laboratory, International Centre for Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy.
School of Cardiovascular Medicine & Sciences, King's College London British Heart Foundation Centre, London, UK.

Hashim Ali (H)

Molecular Medicine Laboratory, International Centre for Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy.
School of Cardiovascular Medicine & Sciences, King's College London British Heart Foundation Centre, London, UK.

Luca Braga (L)

Molecular Medicine Laboratory, International Centre for Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy.
School of Cardiovascular Medicine & Sciences, King's College London British Heart Foundation Centre, London, UK.

Nikoloz Gorgodze (N)

Institute of Life Sciences, Scuola Superiore Sant'Anna, Pisa, Italy.

Fabio Bernini (F)

Institute of Life Sciences, Scuola Superiore Sant'Anna, Pisa, Italy.

Silvia Burchielli (S)

Fondazione Toscana Gabriele Monasterio, Pisa, Italy.

Chiara Collesi (C)

Molecular Medicine Laboratory, International Centre for Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy.
Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.

Lorenzo Zandonà (L)

Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.

Gianfranco Sinagra (G)

Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.

Marcello Piacenti (M)

Fondazione Toscana Gabriele Monasterio, Pisa, Italy.

Serena Zacchigna (S)

Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.
Cardiovascular Biology Laboratory, International Centre for Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy.

Rossana Bussani (R)

Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.

Fabio A Recchia (FA)

Institute of Life Sciences, Scuola Superiore Sant'Anna, Pisa, Italy. fabio.recchia@santannapisa.it.
Fondazione Toscana Gabriele Monasterio, Pisa, Italy. fabio.recchia@santannapisa.it.
Cardiovascular Research Center, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA. fabio.recchia@santannapisa.it.

Mauro Giacca (M)

Molecular Medicine Laboratory, International Centre for Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy. mauro.giacca@kcl.ac.uk.
School of Cardiovascular Medicine & Sciences, King's College London British Heart Foundation Centre, London, UK. mauro.giacca@kcl.ac.uk.
Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy. mauro.giacca@kcl.ac.uk.

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