Microfluidic Chip for Detection of Fungal Infections.

Fungal infections can lead to severe clinical outcomes such as multiple organ failure and septic shock. Rapid detection of fungal infections allows clinicians to treat patients in a timely manner and improves clinical outcomes. Conventional detection methods include blood culture followed by plate culture and polymerase chain reaction. These methods are time-consuming and require expensive equipment, hence, they are not suitable for point-of-care and clinical settings. There is an unmet need to develop a rapid and inexpensive detection method for fungal infections such as candidemia. We developed an innovative immuno-based microfluidic device that can rapidly detect and capture

Déclaration de conflit d'intérêts

The authors declare the following competing financial interest(s): U.D. is a founder of, and has an equity interest in (i) DxNow Inc., a company that is developing microfluidic and imaging technologies, (ii) Koek Biotech, a company that is developing microfluidic IVF technologies for clinical solutions, and (iii) LEVITAS Inc., a company that develops biotechnology tools for genomic analysis in cancer. U.D.' s interests were viewed and managed in accordance with the conflict of interest policies. All other authors declare no conflict of interest.