Oncogenic Effect of the Novel Fusion Gene
Adenocarcinoma of Lung
/ genetics
Amino Acid Sequence
Animals
Apoptosis
/ genetics
Base Sequence
Carcinogenesis
/ genetics
Cell Line, Tumor
Cell Proliferation
/ genetics
Gene Expression Regulation, Neoplastic
Humans
Male
Mice, Nude
Oncogene Proteins, Fusion
/ chemistry
Proto-Oncogene Proteins c-bcl-2
/ genetics
Tumor Stem Cell Assay
Up-Regulation
/ genetics
Xenograft Model Antitumor Assays
VAPA-Rab31
gene fusion
lung adenocarcinoma
tumorigenicity
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
10 May 2019
10 May 2019
Historique:
received:
25
04
2019
revised:
08
05
2019
accepted:
08
05
2019
entrez:
15
5
2019
pubmed:
15
5
2019
medline:
4
9
2019
Statut:
epublish
Résumé
Fusion genes have been identified as oncogenes in several solid tumors including lung, colorectal, and stomach cancers. Here, we characterized the fusion gene,
Identifiants
pubmed: 31083279
pii: ijms20092309
doi: 10.3390/ijms20092309
pmc: PMC6539523
pii:
doi:
Substances chimiques
BCL2 protein, human
0
Oncogene Proteins, Fusion
0
Proto-Oncogene Proteins c-bcl-2
0
VAPA-RAb31 protein, human
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : National Research Foundation of Korea
ID : NRF-2017R1E1A1A01073415
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