High intimal flap mobility assessed by intravascular ultrasound is associated with better short-term results after TEVAR in chronic aortic dissection.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
13 05 2019
Historique:
received: 19 07 2018
accepted: 02 05 2019
entrez: 16 5 2019
pubmed: 16 5 2019
medline: 5 11 2020
Statut: epublish

Résumé

Thoracic endovascular aortic repair (TEVAR) in chronic aortic dissection remains controversial. We analysed whether a high intimal flap mobility (IFM) of the dissection membrane has an impact on aortic remodelling after TEVAR in chronic Type B aortic dissection. Patients undergoing TEVAR with intravascular ultrasound (IVUS) were analysed and IFM was calculated. High IFM was defined as maximum flap amplitude >3 mm. For determining aortic remodelling, the degree of true lumen (TL) expansion was analysed in the last available follow-up CT. Fifty-two patients (63.6 ± 15.4 years) with a mean follow-up of 26.6 ± 20.7 months were analysed. The mobile flap group (n = 29) showed higher absolute TL expansion at the distal stent-graft (5.9 ± 3.1 vs. 3.3 ± 5.4 mm; p = 0.036) and a higher increase in TL diameter (18 ± 10 vs. 9 ± 15%; p = 0.017) compared to the non-mobile group (n = 23). Basic TEVAR-related outcome characteristics were comparable, but the mobile intimal flap group showed a lower re-intervention rate (3 vs. 8pts.; p = 0.032) in chronic dissections. High IFM in chronic Type B aortic dissection is linked to improved aortic remodelling and is associated with a lower re-intervention rate over time. IVUS assessment of IFM in chronic Type B aortic dissection might be helpful in identifying patients with better remodelling after TEVAR.

Identifiants

pubmed: 31086282
doi: 10.1038/s41598-019-43856-6
pii: 10.1038/s41598-019-43856-6
pmc: PMC6513991
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

7267

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Auteurs

Julia Lortz (J)

Department of Cardiology and Vascular Medicine, West- German Heart and Vascular Center Essen, University of Duisburg-Essen, Essen, Germany.

Maria Papathanasiou (M)

Department of Cardiology and Vascular Medicine, West- German Heart and Vascular Center Essen, University of Duisburg-Essen, Essen, Germany.

Christos Rammos (C)

Department of Cardiology and Vascular Medicine, West- German Heart and Vascular Center Essen, University of Duisburg-Essen, Essen, Germany.

Martin Steinmetz (M)

Department of Cardiology and Vascular Medicine, West- German Heart and Vascular Center Essen, University of Duisburg-Essen, Essen, Germany.

Alexander Lind (A)

Department of Cardiology and Vascular Medicine, West- German Heart and Vascular Center Essen, University of Duisburg-Essen, Essen, Germany.

Konstantinos Tsagakis (K)

Department of Thoracic and Cardiovascular Surgery, West- German Heart and Vascular Center Essen, University of Duisburg-Essen, Essen, Germany.

Thomas Schlosser (T)

Department of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.

Heinz Jakob (H)

Department of Thoracic and Cardiovascular Surgery, West- German Heart and Vascular Center Essen, University of Duisburg-Essen, Essen, Germany.

Tienush Rassaf (T)

Department of Cardiology and Vascular Medicine, West- German Heart and Vascular Center Essen, University of Duisburg-Essen, Essen, Germany.

Rolf Alexander Jánosi (RA)

Department of Cardiology and Vascular Medicine, West- German Heart and Vascular Center Essen, University of Duisburg-Essen, Essen, Germany. alexander.janosi@uk-essen.de.

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