Molecular and Cellular Characterization of SIRT1 Allosteric Activators.

ADP-ribose Aging Allosteric activator Deacetylase Deacylase Epigenetics Histone Histone deacetylase (HDAC) Longevity Membrane potential Metabolism Mitochondria NAD+ Nicotinamide Reactive oxygen species (ROS) Recombinant protein Resveratrol SIRT1 Sirtuin Sirtuin-activating compound (STAC) p53

Journal

Methods in molecular biology (Clifton, N.J.)
ISSN: 1940-6029
Titre abrégé: Methods Mol Biol
Pays: United States
ID NLM: 9214969

Informations de publication

Date de publication:
2019
Historique:
entrez: 16 5 2019
pubmed: 16 5 2019
medline: 10 1 2020
Statut: ppublish

Résumé

SIRT1 is an NAD

Identifiants

pubmed: 31087296
doi: 10.1007/978-1-4939-9434-2_8
pmc: PMC6567996
mid: NIHMS1030513
doi:

Substances chimiques

Recombinant Proteins 0
Sirtuin 1 EC 3.5.1.-

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

133-149

Subventions

Organisme : NIDCR NIH HHS
ID : R21 DE027490
Pays : United States
Organisme : NIA NIH HHS
ID : R37 AG028730
Pays : United States
Organisme : NIA NIH HHS
ID : DP1 AG058605
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK100263
Pays : United States
Organisme : NIA NIH HHS
ID : R01 AG019719
Pays : United States

Références

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Auteurs

Michael B Schultz (MB)

Department of Genetics, Blavatnik Institute, Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA, USA.

Conrad Rinaldi (C)

Department of Genetics, Blavatnik Institute, Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA, USA.

Yuancheng Lu (Y)

Department of Genetics, Blavatnik Institute, Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA, USA.

João A Amorim (JA)

Department of Genetics, Blavatnik Institute, Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA, USA.
CNC-Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal.
IIIUC-Institute of Interdisciplinary Research, University of Coimbra, Coimbra, Portugal.

David A Sinclair (DA)

Department of Genetics, Blavatnik Institute, Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA, USA. david_sinclair@hms.harvard.edu.
Department of Pharmacology, School of Medical Sciences, The University of New South Wales, Sydney, NSW, Australia. david_sinclair@hms.harvard.edu.

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Classifications MeSH